derives from/develops from
JURKAT cell
A3 cell
BTO:0001342
BrendaTissueOBO
Human T lymphocyte, acute T cell leukemia cell line. Morphology: lymphoblastoid. The A3 subclone was derived from a Jurkat cell line obtained from the laboratory of Gerald Crabtree at Stanford University. The Jurkat cells were treated with Fas Antibody and isolated by limiting dilution to obtain a cell line that had a low spontaneous rate of resistance to Fas-medicated apoptosis. The resulting wild-type A3 subclone is very sensitive to Fas-mediated apoptosis.
Jurkat A3 cell
Jurkat clone A3 cell