CHEBI:10099 - N-[(benzyloxy)carbonyl]-L-tyrosyl-N-hydroxy-L-leucinamide

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ChEBI Name N-[(benzyloxy)carbonyl]-L-tyrosyl-N-hydroxy-L-leucinamide
ChEBI ID CHEBI:10099
ChEBI ASCII Name N-[(benzyloxy)carbonyl]-L-tyrosyl-N-hydroxy-L-leucinamide
Definition The dipeptide obtained by coupling N-benzyloxycarbonyl-L-tyrosine with the hydroxamic acid derivative of L-leucine. It is an inhibitor of the metallo-protease enzyme, pseudolysin (EC 3.4.24.36).
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Formula C23H29N3O6
Net Charge 0
Average Mass 443.49290
Monoisotopic Mass 443.20564
InChI InChI=1S/C23H29N3O6/c1-15(2)12-19(22(29)26-31)24-21(28)20(13-16-8-10-18(27)11-9-16)25-23(30)32-14-17-6-4-3-5-7-17/h3-11,15,19-20,27,31H,12-14H2,1-2H3,(H,24,28)(H,25,30)(H,26,29)/t19-,20-/m0/s1
InChIKey YBHTVSIBHATTHP-PMACEKPBSA-N
SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OCc1ccccc1)C(=O)NO
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): EC 3.4.24.* (metalloendopeptidase) inhibitor
Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the activity of a metalloendopeptidase (EC 3.4.24.*).
View more via ChEBI Ontology
ChEBI Ontology
Outgoing N-[(benzyloxy)carbonyl]-L-tyrosyl-N-hydroxy-L-leucinamide (CHEBI:10099) has role EC 3.4.24.* (metalloendopeptidase) inhibitor (CHEBI:59107)
N-[(benzyloxy)carbonyl]-L-tyrosyl-N-hydroxy-L-leucinamide (CHEBI:10099) is a dipeptide (CHEBI:46761)
IUPAC Name
N-[(benzyloxy)carbonyl]-L-tyrosyl-N-hydroxy-L-leucinamide
Synonyms Sources
Benzyloxycarbonyl-Tyr-Leu-NHOH KEGG COMPOUND
Cbz-Tyr-Leu-NHOH KEGG COMPOUND
N-[(benzyloxy)carbonyl]-L-tyrosyl-L-leucine hydroxamic acid ChEBI
Z-L-Tyr-L-Leu-NHOH ChEBI
Z-Tyr-Leu-NHOH KEGG COMPOUND
Manual Xref Database
C02203 KEGG COMPOUND
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Last Modified
04 August 2014