N-(2-bromo-11H-pyrido[1,2-b][2,4]benzodiazepin-6-ylidene)benzenesulfonamide (CHEBI:105860)

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ChEBI Name	N-(2-bromo-11H-pyrido[1,2-b][2,4]benzodiazepin-6-ylidene)benzenesulfonamide

ChEBI ID	CHEBI:105860

Stars	This entity has been manually annotated by a third party.

Supplier Information

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Formula

C19H14BrN3O2S

Net Charge

Average Mass

428.304

Monoisotopic Mass

426.99901

InChI

InChI=1S/C19H14BrN3O2S/c20-15-10-11-18-21-19(22-26(24,25)16-7-2-1-3-8-16)17-9-5-4-6-14(17)12-23(18)13-15/h1-11,13H,12H2

InChIKey

AUPBGTHXQXUXTF-UHFFFAOYSA-N

SMILES

C1C2=CC=CC=C2C(=NS(=O)(=O)C3=CC=CC=C3)N=C4N1C=C(C=C4)Br

Roles Classification
Biological Role(s):	GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. (via benzodiazepine )

Application(s):	GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. (via benzodiazepine )

ChEBI Ontology
Outgoing	N-(2-bromo-11H-pyrido[1,2-b][2,4]benzodiazepin-6-ylidene)benzenesulfonamide (CHEBI:105860) is a benzodiazepine (CHEBI:22720)