CHEBI:10588 - 1-(3-chlorophenyl)piperazine

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ChEBI Name 1-(3-chlorophenyl)piperazine
ChEBI ID CHEBI:10588
Definition A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information No supplier information found for this compound.
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para-Cresol, also 4-methylphenol, is an organic compound with the formula CH3C6H4(OH). It is a colourless solid that is widely used intermediate in the production of other chemicals. It is a derivative of phenol and is an isomer of o-cresol and m-cresol.
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Formula C10H13ClN2
Net Charge 0
Average Mass 196.67640
Monoisotopic Mass 196.07673
InChI InChI=1S/C10H13ClN2/c11-9-2-1-3-10(8-9)13-6-4-12-5-7-13/h1-3,8,12H,4-7H2
InChIKey VHFVKMTVMIZMIK-UHFFFAOYSA-N
SMILES Clc1cccc(c1)N1CCNCC1
Roles Classification
Chemical Role(s): environmental contaminant
Any minor or unwanted substance introduced into the environment that can have undesired effects.
Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): drug metabolite

serotonergic agonist
An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.
xenobiotic
A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
Application(s): serotonergic agonist
An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.
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ChEBI Ontology
Outgoing 1-(3-chlorophenyl)piperazine (CHEBI:10588) has role drug metabolite (CHEBI:49103)
1-(3-chlorophenyl)piperazine (CHEBI:10588) has role environmental contaminant (CHEBI:78298)
1-(3-chlorophenyl)piperazine (CHEBI:10588) has role serotonergic agonist (CHEBI:35941)
1-(3-chlorophenyl)piperazine (CHEBI:10588) has role xenobiotic (CHEBI:35703)
1-(3-chlorophenyl)piperazine (CHEBI:10588) is a N-arylpiperazine (CHEBI:46848)
1-(3-chlorophenyl)piperazine (CHEBI:10588) is a monochlorobenzenes (CHEBI:83403)
IUPAC Name
1-(3-chlorophenyl)piperazine
Synonyms Sources
(m-CPP) HMDB
1-(3-Chlorophenyl)piperazine KEGG COMPOUND
m-Chlorophenylpiperazine KEGG COMPOUND
Manual Xrefs Databases
C11738 KEGG COMPOUND
HMDB0061008 HMDB
LSM-25627 LINCS
Meta-Chlorophenylpiperazine Wikipedia
View more database links
Registry Numbers Types Sources
6640-24-0 CAS Registry Number KEGG COMPOUND
6640-24-0 CAS Registry Number ChemIDplus
8409 Reaxys Registry Number Reaxys
Citations Types Sources
11311791 PubMed citation Europe PMC
18621591 PubMed citation Europe PMC
23768699 PubMed citation Europe PMC
24062697 PubMed citation Europe PMC
6827905 PubMed citation Europe PMC
Last Modified
25 February 2016