nomifensine (CHEBI:116225)

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ChEBI Name	nomifensine

ChEBI ID	CHEBI:116225

Definition	An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formula

C16H18N2

Net Charge

Average Mass

238.32750

Monoisotopic Mass

238.14700

InChI

InChI=1S/C16H18N2/c1-18-10-14(12-6-3-2-4-7-12)13-8-5-9-16(17)15(13)11-18/h2-9,14H,10-11,17H2,1H3

InChIKey

XXPANQJNYNUNES-UHFFFAOYSA-N

SMILES

CN1CC(c2ccccc2)c2cccc(N)c2C1

Roles Classification
Biological Role(s):	dopamine uptake inhibitor A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.

Application(s):	dopamine uptake inhibitor A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.

ChEBI Ontology
Outgoing	nomifensine (CHEBI:116225) has role dopamine uptake inhibitor (CHEBI:51039) nomifensine (CHEBI:116225) is a isoquinolines (CHEBI:24922)

Incoming	(R)-nomifensine (CHEBI:521391) is a nomifensine (CHEBI:116225) (S)-nomifensine (CHEBI:180847) is a nomifensine (CHEBI:116225)

IUPAC Name

2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine

Synonyms	Sources
(+-)-Nomifensin	ChemIDplus
(+-)-Nomifensine	ChemIDplus
2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine	ChEBI
8-Amino-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline	ChemIDplus
D,L-nomifensine	ChEBI
Nomifenison	NIST Chemistry WebBook
Nomifensin	NIST Chemistry WebBook
Nomifensine	NIST Chemistry WebBook
Nomiphensine	NIST Chemistry WebBook
R/S-nomifensine	ChEBI

Last Modified

22 February 2017