galgravin (CHEBI:132648)

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ChEBI Name	galgravin

ChEBI ID	CHEBI:132648

Definition	A member of the class of aryltetrahydrofurans carrying two 3,4-dimethoxyphenyl substituents at positions 2 and 5 as well as two methyl groups at positions 3 and 4.

Stars	This entity has been manually annotated by the ChEBI Team.

Submitter	qingping liu

Supplier Information

Download	Molfile XML SDF

Formula

C22H28O5

Net Charge

Average Mass

372.456

Monoisotopic Mass

372.19367

InChI

InChI=1S/C22H28O5/c1-13-14(2)22(16-8-10-18(24-4)20(12-16)26-6)27-21(13)15-7-9-17(23-3)19(11-15)25-5/h7-14,21-22H,1-6H3/t13-,14+,21-,22+

InChIKey

JLJAVUZBHSLLJL-DQEHQXCCSA-N

SMILES

C1(=C(C=CC(=C1)[C@@H]2O[C@@H]([C@H]([C@H]2C)C)C3=CC=C(C(=C3)OC)OC)OC)OC

Metabolite of Species	Details
Acorus tatarinowii (NCBI:txid123564)	Found in rhizome (BTO:0001181). See: PubMed
Schisandra propinqua (NCBI:txid124790)	Found in stem (BTO:0001300). See: PubMed
Piper mullesua (NCBI:txid126644)	See: PubMed
Machilus thunbergii (NCBI:txid128685)	Found in bark (BTO:0001301). See: PubMed
Aristolochia arcuata (NCBI:txid158533)	See: PubMed
Piper wallichii (NCBI:txid450288)	See: PubMed
Nectandra megapotamica (NCBI:txid881593)	See: PubMed
Nectandra megapotamica (NCBI:txid881593)	Found in leaf (BTO:0000713). See: PubMed
Nectandra rigida (NCBI:txid881595)	See: PubMed

Roles Classification
Biological Role(s):	plant metabolite Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.

Application(s):	bone density conservation agent An agent that inhibits bone resorption and/or favor bone mineralization and bone regeneration. Used to heal bone fractures and to treat bone diseases such as osteopenia and osteoporosis. neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders. platelet aggregation inhibitor A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.

ChEBI Ontology
Outgoing	galgravin (CHEBI:132648) has role bone density conservation agent (CHEBI:50646) galgravin (CHEBI:132648) has role neuroprotective agent (CHEBI:63726) galgravin (CHEBI:132648) has role plant metabolite (CHEBI:76924) galgravin (CHEBI:132648) has role platelet aggregation inhibitor (CHEBI:50427) galgravin (CHEBI:132648) is a aryltetrahydrofuran (CHEBI:47021) galgravin (CHEBI:132648) is a dimethoxybenzene (CHEBI:51681) galgravin (CHEBI:132648) is a lignan (CHEBI:25036) galgravin (CHEBI:132648) is a ring assembly (CHEBI:36820)

IUPAC Name

(2R,3R,4S,5S)-2,5-bis(3,4-dimethoxyphenyl)-3,4-dimethyloxolane

Last Modified

20 May 2022