iomazenil ((123)I) (CHEBI:135665)

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ChEBI Name	iomazenil (¹²³I)

ChEBI ID	CHEBI:135665

ChEBI ASCII Name	iomazenil ((123)I)

Stars	This entity has been manually annotated by a third party.

Supplier Information

Download	Molfile XML SDF

Formula

C15H14[123I]N3O3

Net Charge

Average Mass

407.201

Monoisotopic Mass

407.00911

InChI

InChI=1S/C15H14IN3O3/c1-3-22-15(21)13-11-7-18(2)14(20)12-9(16)5-4-6-10(12)19(11)8-17-13/h4-6,8H,3,7H2,1-2H3/i16-4

InChIKey

FRIZVHMAECRUBR-KIWWSDKQSA-N

SMILES

C(OCC)(=O)C1=C2N(C=N1)C=3C(C(N(C2)C)=O)=C([123I])C=CC3

Roles Classification
Biological Role(s):	GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. (via benzodiazepine )

Application(s):	GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. (via benzodiazepine )

ChEBI Ontology
Outgoing	iomazenil (¹²³I) (CHEBI:135665) is a imidazobenzodiazepine (CHEBI:142118)

Synonym	Source
iomazenil	DrugCentral

Registry Number	Type	Source
127396-36-5	CAS Registry Number	DrugCentral

Last Modified

06 September 2018