tafenoquine (CHEBI:135752)

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ChEBI Name	tafenoquine

ChEBI ID	CHEBI:135752

Definition	A racemate comprising equimolar amounts of (R)- and (S)-tafenoquine.

Stars	This entity has been manually annotated by the ChEBI Team.

Wikipedia	License

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Formula

C24H28F3N3O3

Net Charge

Average Mass

463.494

Monoisotopic Mass

463.20828

Roles Classification
Biological Role(s):	antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. antileishmanial agent An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania. trypanocidal drug A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida. apoptosis inducer Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.

Application(s):	antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. antileishmanial agent An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania. trypanocidal drug A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida.

ChEBI Ontology
Outgoing	tafenoquine (CHEBI:135752) has part (R)-tafenoquine (CHEBI:141488) tafenoquine (CHEBI:135752) has part (S)-tafenoquine (CHEBI:141489) tafenoquine (CHEBI:135752) has role antileishmanial agent (CHEBI:70868) tafenoquine (CHEBI:135752) has role antimalarial (CHEBI:38068) tafenoquine (CHEBI:135752) has role apoptosis inducer (CHEBI:68495) tafenoquine (CHEBI:135752) has role trypanocidal drug (CHEBI:36335) tafenoquine (CHEBI:135752) is a racemate (CHEBI:60911)

IUPAC Name

rac-N⁴-{2,6-dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl}pentane-1,4-diamine

Last Modified

29 August 2018