CHEBI:135754 - loprazolam

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name loprazolam
ChEBI ID CHEBI:135754
Stars This entity has been manually annotated by a third party.
Supplier Information
Download Molfile XML SDF
Formula C23H21ClN6O3
Net Charge 0
Average Mass 464.905
Monoisotopic Mass 464.13637
InChI InChI=1S/C23H21ClN6O3/c1-27-8-10-28(11-9-27)14-19-23(31)29-20-7-6-15(30(32)33)12-17(20)22(25-13-21(29)26-19)16-4-2-3-5-18(16)24/h2-7,12,14H,8-11,13H2,1H3/b19-14-
InChIKey UTEFBSAVJNEPTR-RGEXLXHISA-N
SMILES O=C/1N2C=3C(C(=NCC2=N\C1=C/N4CCN(CC4)C)C5=C(Cl)C=CC=C5)=CC(=CC3)[N+](=O)[O-]
Roles Classification
Biological Role(s): GABA modulator
A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
(via benzodiazepine )
Application(s): GABA modulator
A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
(via benzodiazepine )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing loprazolam (CHEBI:135754) is a imidazobenzodiazepine (CHEBI:142118)
Synonyms Sources
loprazolam mesilate DrugCentral
loprazolam mesylate DrugCentral
Manual Xref Database
1602 DrugCentral
View more database links
Registry Number Type Source
61197-73-7 CAS Registry Number DrugCentral
Last Modified
05 September 2018