CHEBI:140243 - 22-hydroxyprotectin D1

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ChEBI Name 22-hydroxyprotectin D1
ChEBI ID CHEBI:140243
Definition A docosanoid that is protectin D1 in which one of the terminal methyl hydrogens has been replaced by a hydroxy group. An intermediate of specialised proresolving mediators
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Bijay
Supplier Information ZINC000015149528
Download Molfile XML SDF
Formula C22H32O5
Net Charge 0
Average Mass 376.487
Monoisotopic Mass 376.22497
InChI InChI=1S/C22H32O5/c23-19-13-7-11-17-21(25)16-10-6-5-9-15-20(24)14-8-3-1-2-4-12-18-22(26)27/h2-11,15-16,20-21,23-25H,1,12-14,17-19H2,(H,26,27)/b4-2-,6-5+,8-3-,11-7-,15-9+,16-10-/t20-,21-/m1/s1
InChIKey RXZULUQRGUAOLG-OCDBVANQSA-N
SMILES OC(CC/C=C\C/C=C\C[C@H](\C=C\C=C\C=C/[C@H](C/C=C\CCO)O)O)=O
Metabolite of Species Details
Homo sapiens (NCBI:txid9606) See: PubMed
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): specialised pro-resolving mediator
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
human xenobiotic metabolite
Any human metabolite produced by metabolism of a xenobiotic compound in humans.
Application(s): specialised pro-resolving mediator
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
anti-inflammatory agent
Any compound that has anti-inflammatory effects.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing 22-hydroxyprotectin D1 (CHEBI:140243) has functional parent protectin D1 (CHEBI:138655)
22-hydroxyprotectin D1 (CHEBI:140243) has role anti-inflammatory agent (CHEBI:67079)
22-hydroxyprotectin D1 (CHEBI:140243) has role human xenobiotic metabolite (CHEBI:76967)
22-hydroxyprotectin D1 (CHEBI:140243) has role specialised pro-resolving mediator (CHEBI:140399)
22-hydroxyprotectin D1 (CHEBI:140243) is a ω-hydroxy-long-chain fatty acid (CHEBI:140997)
22-hydroxyprotectin D1 (CHEBI:140243) is a docosanoid (CHEBI:131863)
22-hydroxyprotectin D1 (CHEBI:140243) is a hydroxy polyunsaturated fatty acid (CHEBI:140345)
22-hydroxyprotectin D1 (CHEBI:140243) is a protectin (CHEBI:193572)
22-hydroxyprotectin D1 (CHEBI:140243) is conjugate acid of 22-hydroxyprotectin D1(1−) (CHEBI:140348)
Incoming 22-hydroxyprotectin D1(1−) (CHEBI:140348) is conjugate base of 22-hydroxyprotectin D1 (CHEBI:140243)
IUPAC Name
(4Z,7Z,10R,11E,13E,15Z,17S,19Z)-10,17,22-trihydroxydocosa-4,7,11,13,15,19-hexaenoic acid
Synonyms Sources
(4Z,7Z,10R,11E,13E,15Z,17S,19Z)-10,17,22-trihydroxydocosahexaenoic acid ChEBI
10(R),17(S),20-trihydroxydocosa-4Z,7Z,11E,13E,15Z,19Z-hexaenoic acid ChEBI
22-hydroxy-(neuro)protectin D1 ChEBI
22-hydroxyneuroprotectin D1 ChEBI
22-OH-(N)PD1 SUBMITTER
22-OH-PD1 ChEBI
Registry Number Type Source
27632053 Reaxys Registry Number Reaxys
Citation
Last Modified
24 January 2023