CHEBI:142183 - (2S)-1-(6-chloro-5-fluoroindol-1-yl)-propan-2-amine

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ChEBI Name (2S)-1-(6-chloro-5-fluoroindol-1-yl)-propan-2-amine ChEBI ID CHEBI:142183 ChEBI ASCII Name (2S)-1-(6-chloro-5-fluoroindol-1-yl)-propan-2-amine Definition A 1-(6-chloro-5-fluoroindol-1-yl)-propan-2-amine that has S configuration. A selective agonist for both the 5-hydroxytryptamine 2B (5-HT2B) and 5-hydroxytryptamine 2C (5-HT2C)serotonin receptor subtypes, commonly used as fumarate salt. Stars This entity has been manually annotated by the ChEBI Team. Supplier Information Download Molfile XML SDF Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search Wikipedia License Read full article at Wikipedia Formula C11H12ClFN2 Net Charge 0 Average Mass 226.678 Monoisotopic Mass 226.06730 InChI InChI=1S/C11H12ClFN2/c1-7(14)6-15-3-2-8-4-10(13)9(12)5-11(8)15/h2-5,7H,6,14H2,1H3/t7-/m0/s1 InChIKey XJJZQXUGLLXTHO-ZETCQYMHSA-N SMILES C[C@@H](CN1C=CC2=CC(=C(C=C21)Cl)F)N Roles Classification Chemical Role(s): Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). (via organic amino compound ) Biological Role(s): 5-hydroxytryptamine 2B receptor agonist An agonist at the 5-hydroxytryptamine 2B (5-HT2B) receptor. 5-hydroxytryptamine 2C receptor agonist An agonist at the 5-hydroxytryptamine 2B (5-HT2C) receptor. View more via ChEBI Ontology ChEBI Ontology Outgoing (2S)-1-(6-chloro-5-fluoroindol-1-yl)-propan-2-amine (CHEBI:142183) has role 5-hydroxytryptamine 2B receptor agonist (CHEBI:142184) (2S)-1-(6-chloro-5-fluoroindol-1-yl)-propan-2-amine (CHEBI:142183) has role 5-hydroxytryptamine 2C receptor agonist (CHEBI:142185) (2S)-1-(6-chloro-5-fluoroindol-1-yl)-propan-2-amine (CHEBI:142183) is a 1-(6-chloro-5-fluoroindol-1-yl)-propan-2-amine (CHEBI:91736) IUPAC Name (2S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine Synonyms Sources (1S)-2-(6-chloro-5-fluoroindol-1-yl)-1-methylethylamine ChEBI (S)-2-(6-chloro-5-fluoro-indol-1-yl)-1-methyl-ethylamine ChEBI (S)-2-(6-chloro-5-fluoroindol-1-yl)-1-methylethylamine ChEBI (S)-6-chloro-5-fluoro-α-methyl-1H-indole-1-ethanamine ChEBI ORG 35030 ChEBI Ro 60-0175 ChEBI Ro-60-0175 ChEBI Ro60-0175 ChEBI Manual Xrefs Databases EP655440 Patent LSM-1601 LINCS Ro60-0175 Wikipedia View more database links Registry Number Type Source 7795121 Reaxys Registry Number Reaxys Citations Types Sources 10219979 PubMed citation Europe PMC 10498829 PubMed citation Europe PMC 10814735 PubMed citation Europe PMC 10903970 PubMed citation Europe PMC 11105935 PubMed citation Europe PMC 11399662 PubMed citation Europe PMC 12604698 PubMed citation Europe PMC 14666118 PubMed citation Europe PMC 17473916 PubMed citation Europe PMC 17653111 PubMed citation Europe PMC 22342986 PubMed citation Europe PMC 23201361 PubMed citation Europe PMC 23535834 PubMed citation Europe PMC 28583411 PubMed citation Europe PMC 9225301 PubMed citation Europe PMC 9694950 PubMed citation Europe PMC Last Modified 11 September 2018