N-[1-(methanesulfonyl)piperidin-4-yl]-N'-[4-(trifluoromethoxy)phenyl]urea (CHEBI:142793)

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ChEBI Name	N-[1-(methanesulfonyl)piperidin-4-yl]-N'-[4-(trifluoromethoxy)phenyl]urea

ChEBI ID	CHEBI:142793

ChEBI ASCII Name	N-[1-(methanesulfonyl)piperidin-4-yl]-N'-[4-(trifluoromethoxy)phenyl]urea

Definition	A phenylurea that is urea substituted by 1-(methylsulfonyl)piperidin-4-yl and 4-(trifluoromethoxy)phenyl groups at positions 1 and 3 respectively.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formula

C14H18F3N3O4S

Net Charge

Average Mass

381.372

Monoisotopic Mass

381.09701

InChI

InChI=1S/C14H18F3N3O4S/c1-25(22,23)20-8-6-11(7-9-20)19-13(21)18-10-2-4-12(5-3-10)24-14(15,16)17/h2-5,11H,6-9H2,1H3,(H2,18,19,21)

InChIKey

YORLNOBDSZJFQQ-UHFFFAOYSA-N

SMILES

C(NC1=CC=C(C=C1)OC(F)(F)F)(NC2CCN(CC2)S(=O)(=O)C)=O

Roles Classification
Biological Role(s):	EC 3.3.2.10 (soluble epoxide hydrolase) inhibitor Any inhibitor of soluble epoxide hydrolase, a bifunctional enzyme that in humans is encoded by the EPHX2 gene.Found in both the cytosol and peroxisomes it binds to specific epoxides and converts them into the corresponding diols.

ChEBI Ontology
Outgoing	N-[1-(methanesulfonyl)piperidin-4-yl]-N'-[4-(trifluoromethoxy)phenyl]urea (CHEBI:142793) has role EC 3.3.2.10 (soluble epoxide hydrolase) inhibitor (CHEBI:142790) N-[1-(methanesulfonyl)piperidin-4-yl]-N'-[4-(trifluoromethoxy)phenyl]urea (CHEBI:142793) is a phenylureas (CHEBI:134043)

Synonyms	Sources
N-(1-mesylpiperidin-4-yl)-N'-[4-(trifluoromethoxy)phenyl]urea	ChEBI
N-[1-(methylsulfonyl)piperidin-4-yl]-N'-[4-(trifluoromethoxy)phenyl]urea	ChEBI
sEHi, #1709	ChEBI

Citation	Type	Source
30033524	PubMed citation	Europe PMC

Last Modified

14 December 2018