CHEBI:176788 - dizocilpine maleate

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ChEBI Name dizocilpine maleate
ChEBI ID CHEBI:176788
Definition A maleate salt obtained by reaction of dizocilpine with one equivalent of maleic acid.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C16H15N.C4H4O4
Net Charge 0
Average Mass 337.375
Monoisotopic Mass 337.13141
InChI InChI=1S/C16H15N.C4H4O4/c1-16-13-8-4-2-6-11(13)10-15(17-16)12-7-3-5-9-14(12)16;5-3(6)1-2-4(7)8/h2-9,15,17H,10H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t15-,16+;/m1./s1
InChIKey QLTXKCWMEZIHBJ-PJGJYSAQSA-N
SMILES OC(=O)\C=C/C(O)=O.[H][C@]12CC3=C(C=CC=C3)[C@](C)(N1)C1=C2C=CC=C1
Roles Classification
Biological Role(s): nicotinic antagonist
An antagonist at the nicotinic cholinergic receptor.
NMDA receptor antagonist
Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs.
Application(s): anaesthetic
Substance which produces loss of feeling or sensation.
anticonvulsant
A drug used to prevent seizures or reduce their severity.
neuroprotective agent
Any compound that can be used for the treatment of neurodegenerative disorders.
nicotinic antagonist
An antagonist at the nicotinic cholinergic receptor.
antidepressant
Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
(via tetracyclic antidepressant )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing dizocilpine maleate (CHEBI:176788) has part dizocilpine(1+) (CHEBI:176787)
dizocilpine maleate (CHEBI:176788) has role anaesthetic (CHEBI:38867)
dizocilpine maleate (CHEBI:176788) has role anticonvulsant (CHEBI:35623)
dizocilpine maleate (CHEBI:176788) has role neuroprotective agent (CHEBI:63726)
dizocilpine maleate (CHEBI:176788) has role nicotinic antagonist (CHEBI:48878)
dizocilpine maleate (CHEBI:176788) has role NMDA receptor antagonist (CHEBI:60643)
dizocilpine maleate (CHEBI:176788) is a maleate salt (CHEBI:50221)
dizocilpine maleate (CHEBI:176788) is a tetracyclic antidepressant (CHEBI:50940)
IUPAC Name
(5S,10R)-5-methyl-10,11-dihydro-5H-5,10-epiminodibenzo[a,d][7]annulene (2Z)-but-2-enedioate
Synonyms Sources
MK 801 ChemIDplus
MK-801 ChemIDplus
Manual Xref Database
D03878 KEGG DRUG
View more database links
Registry Number Type Source
77086-22-7 CAS Registry Number ChemIDplus
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Last Modified
09 July 2021