CHEBI:183514 - psora 4

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ChEBI Name psora 4
ChEBI ID CHEBI:183514
Definition A member of the class of psoralens that is psoralen substituted by a 4-phenylbutoxy group at position 5. It is a potent inhibitor of the voltage-gated potassium channel Kv1.3 (EC50 = 3 nM).
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C21H18O4
Net Charge 0
Average Mass 334.371
Monoisotopic Mass 334.12051
InChI InChI=1S/C21H18O4/c22-20-10-9-16-19(25-20)14-18-17(11-13-23-18)21(16)24-12-5-4-8-15-6-2-1-3-7-15/h1-3,6-7,9-11,13-14H,4-5,8,12H2
InChIKey JJAWGNIQEOFURP-UHFFFAOYSA-N
SMILES O=C1OC2=CC3=C(C=CO3)C(OCCCCC3=CC=CC=C3)=C2C=C1
Roles Classification
Biological Role(s): potassium channel blocker
An agent that inhibits cell membrane glycoproteins that are selectively permeable to potassium ions.
immunosuppressive agent
An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
Application(s): geroprotector
Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
immunosuppressive agent
An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing psora 4 (CHEBI:183514) has role geroprotector (CHEBI:176497)
psora 4 (CHEBI:183514) has role immunosuppressive agent (CHEBI:35705)
psora 4 (CHEBI:183514) has role potassium channel blocker (CHEBI:50509)
psora 4 (CHEBI:183514) is a aromatic ether (CHEBI:35618)
psora 4 (CHEBI:183514) is a benzenes (CHEBI:22712)
psora 4 (CHEBI:183514) is a psoralens (CHEBI:26369)
IUPAC Name
4-(4-phenylbutoxy)-7H-furo[3,2-g]chromen-7-one
Synonyms Sources
4-(4-phenylbutoxy)-7H-furo[3,2-g][1]benzopyran-7-one IUPAC
5-(4-phenylbutoxy)psoralen ChEBI
psora-4 ChEBI
Manual Xrefs Databases
5036283 ChemSpider
HMDB0256900 HMDB
View more database links
Registry Number Type Source
724709-68-6 CAS Registry Number ChEBI
Citations Waiting for Citations Types Sources
15155830 PubMed citation Europe PMC
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Last Modified
09 November 2021