3-methyl-3,4-dihydro-1h-1,4-benzodiazepine-2,5-dione (CHEBI:190989)

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ChEBI Name	3-methyl-3,4-dihydro-1h-1,4-benzodiazepine-2,5-dione

ChEBI ID	CHEBI:190989

Stars	This entity has been manually annotated by a third party.

Submitter	MetaboLights

Supplier Information

Download	Molfile XML SDF

Formula

C10H10N2O2

Net Charge

Average Mass

190.202

Monoisotopic Mass

190.07423

InChI

InChI=1S/C10H10N2O2/c1-6-9(13)12-8-5-3-2-4-7(8)10(14)11-6/h2-6H,1H3,(H,11,14)(H,12,13)

InChIKey

LJONQULKOKMKBR-UHFFFAOYSA-N

SMILES

O=C1NC=2C(C(=O)NC1C)=CC=CC2

Metabolite of Species	Details
Rattus norvegicus (NCBI:txid10116)	Found in INS-1 cell (BTO:0002135). See: MetaboLights Study

Roles Classification
Biological Role(s):	GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. (via benzodiazepine )

Application(s):	GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. (via benzodiazepine )

ChEBI Ontology
Outgoing	3-methyl-3,4-dihydro-1h-1,4-benzodiazepine-2,5-dione (CHEBI:190989) is a benzodiazepine (CHEBI:22720)

IUPAC Name

3-methyl-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione