5-fluoromethylornithine (CHEBI:195324)

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ChEBI Name	5-fluoromethylornithine

ChEBI ID	CHEBI:195324

Definition	An ornithine derivative in which one of the hydrogens at position 5 is replaced by a fluoromethyl group. It is an irreversible inhibitor of ornithine aminotransferase.

Stars	This entity has been manually annotated by the ChEBI Team.

Submitter	Doug Howe

Supplier Information

Download	Molfile XML SDF

Formula

C6H13FN2O2

Net Charge

Average Mass

164.180

Monoisotopic Mass

164.09611

InChI

InChI=1S/C6H13FN2O2/c7-3-4(8)1-2-5(9)6(10)11/h4-5H,1-3,8-9H2,(H,10,11)

InChIKey

PRNUWRQQLDXHRZ-UHFFFAOYSA-N

SMILES

NC(CF)CCC(N)C(O)=O

Roles Classification
Biological Role(s):	EC 2.6.1.13 (ornithine aminotransferase) inhibitor An EC 2.6.1.* (transaminase) inhibitor that interferes with the action of ornithine aminotransferase (EC 2.6.1.13).

ChEBI Ontology
Outgoing	5-fluoromethylornithine (CHEBI:195324) has role EC 2.6.1.13 (ornithine aminotransferase) inhibitor (CHEBI:195331) 5-fluoromethylornithine (CHEBI:195324) is a organofluorine compound (CHEBI:37143) 5-fluoromethylornithine (CHEBI:195324) is a ornithine derivative (CHEBI:25718)

IUPAC Name

5-amino-6-fluoronorleucine

Synonyms	Sources
2,5-diamino-6-fluorohexanoic acid	IUPAC
5-FMOrn	ChEBI
5FMOrn	ChEBI

Registry Number	Type	Source
116292-10-5	CAS Registry Number	ChEBI

Last Modified

03 July 2023