carbovir (CHEBI:202940)

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ChEBI Name	carbovir

ChEBI ID	CHEBI:202940

Definition	Cyclopent-2-en-1-ylmethanol in which the 4-position is substituted by a 2-amino-6-hydroxy-9H-purin-9-yl group such that the two substitutents on the cyclopentene ring are in a cis relationship. The (−)-enantiomer, also known as carbovir, is a potent inhibitor of HIV replication replication in cell cultures.

Stars	This entity has been manually annotated by the ChEBI Team.

Roles Classification
Biological Role(s):	HIV-1 reverse transcriptase inhibitor An entity which inhibits the activity of HIV-1 reverse transcriptase.

ChEBI Ontology
Outgoing	carbovir (CHEBI:202940) has role HIV-1 reverse transcriptase inhibitor (CHEBI:53756) carbovir (CHEBI:202940) is a 2-aminopurines (CHEBI:20702)

Incoming	(−)-carbovir (CHEBI:421843) is a carbovir (CHEBI:202940)

IUPAC Name

2-amino-9-[rel-(1R,4S)-4-(hydroxymethyl)cyclopent-2-en-1-yl]-1,9-dihydro-6H-purin-6-one

Synonyms	Sources
(±)-carbovir	ChEBI
2-amino-9-[rel-(1R,4S)-4-(hydroxymethyl)cyclopent-2-en-1-yl]-9H-purin-6-ol	IUPAC
carbovir	ChemIDplus
cis-(±)-2-amino-1,9-dihydro-9-(4-(hydroxymethyl)-2-cyclopenten-1-yl)-6H-purin-6-one	ChEBI
cis-2-amino-1,9-dihydro-9-(4-(hydroxymethyl)-2-cyclopenten-1-yl)-6H-purin-6-one	ChEBI
cis-2-amino-9-(4-hydroxymethylcyclopent-2-enyl)-9H-purin-6-ol	ChEBI

Registry Number	Type	Source
118353-05-2	CAS Registry Number	ChemIDplus

Last Modified

27 September 2010