CHEBI:204734 - desonide

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ChEBI Name desonide ChEBI ID CHEBI:204734 Definition Triamcinolone acetonide with hydrogen instead of the fluorine substituent at position 9. A corticosteroid anti-inflammatory, it is used topically as a cream, ointment or lotion for the treatment of various skin disorders. Stars This entity has been manually annotated by the ChEBI Team. Supplier Information Download Molfile XML SDF Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search Wikipedia License Read full article at Wikipedia Formula C24H32O6 Net Charge 0 Average Mass 416.50730 Monoisotopic Mass 416.21989 InChI InChI=1S/C24H32O6/c1-21(2)29-19-10-16-15-6-5-13-9-14(26)7-8-22(13,3)20(15)17(27)11-23(16,4)24(19,30-21)18(28)12-25/h7-9,15-17,19-20,25,27H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,20+,22-,23-,24+/m0/s1 InChIKey WBGKWQHBNHJJPZ-LECWWXJVSA-N SMILES [H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]1(C)[C@@]2([H])C[C@H]2OC(C)(C)O[C@@]12C(=O)CO Roles Classification Application(s): anti-inflammatory drug A substance that reduces or suppresses inflammation. View more via ChEBI Ontology ChEBI Ontology Outgoing desonide (CHEBI:204734) has role anti-inflammatory drug (CHEBI:35472) desonide (CHEBI:204734) is a 11β-hydroxy steroid (CHEBI:35346) desonide (CHEBI:204734) is a 20-oxo steroid (CHEBI:36885) desonide (CHEBI:204734) is a 21-hydroxy steroid (CHEBI:35344) desonide (CHEBI:204734) is a 3-oxo-Δ1,Δ4-steroid (CHEBI:77166) desonide (CHEBI:204734) is a corticosteroid (CHEBI:50858) desonide (CHEBI:204734) is a cyclic ketal (CHEBI:59779) desonide (CHEBI:204734) is a primary α-hydroxy ketone (CHEBI:139590) IUPAC Name (4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one INNs Sources desonida ChemIDplus desonide ChemIDplus desonidum ChemIDplus Synonyms Sources 11β,21-dihydroxy-16α,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione ChEBI 11β,21-dihydroxy-16α,17-isopropylidenedioxypregna-1,4-diene-3,20-dione ChEBI 11β,21-dihydroxy-16α,17α-isopropylidenedioxypregna-1,4-diene-3,20-dione ChEBI 16α,17α-isopropylidenedioxyprednisolone ChEBI 16α-hydroxyprednisole-16,17-acetonide ChemIDplus 16α-hydroxyprednisolone-16α,17-acetonide ChEBI desfluorotriamcinolone acetonide ChEBI Manual Xrefs Databases 3135 DrugCentral D03696 KEGG DRUG DB01260 DrugBank Desonide Wikipedia US2990401 Patent US3536586 Patent US3549498 Patent View more database links Registry Numbers Types Sources 56987 Beilstein Registry Number Beilstein 638-94-8 CAS Registry Number ChemIDplus 638-94-8 CAS Registry Number KEGG DRUG Citations Types Sources 3783574 PubMed citation ChEMBL 6827553 PubMed citation ChEMBL Last Modified 06 February 2018