CHEBI:228346 - ulotaront

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ChEBI Name ulotaront
ChEBI ID CHEBI:228346
Definition A member of the class of thienopyrans that is 4,7-dihydro-5H-thieno[2,3-c]pyran substituted by a (methylamino)methyl at position 7S. It is a trace amine-associated receptor 1 and serotonin 5-HT1A receptors agonist that has demonstrated efficacy in the treatment of patients with schizophrenia.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C9H13NOS
Net Charge 0
Average Mass 183.270
Monoisotopic Mass 183.07179
InChI InChI=1S/C9H13NOS/c1-10-6-8-9-7(2-4-11-8)3-5-12-9/h3,5,8,10H,2,4,6H2,1H3/t8-/m0/s1
InChIKey ABDDQTDRAHXHOC-QMMMGPOBSA-N
SMILES CNC[C@@H]1OCCC2=C1SC=C2
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): trace amine-associated receptor 1 agonist
An agonist that selectively binds to and activates trace amine-associated receptor 1.
serotonergic agonist
An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.
Application(s): psychotropic drug
A loosely defined grouping of drugs that have effects on psychological function.
antidepressant
Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
antipsychotic agent
Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
serotonergic agonist
An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.
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ChEBI Ontology
Outgoing ulotaront (CHEBI:228346) has role antidepressant (CHEBI:35469)
ulotaront (CHEBI:228346) has role antipsychotic agent (CHEBI:35476)
ulotaront (CHEBI:228346) has role psychotropic drug (CHEBI:35471)
ulotaront (CHEBI:228346) has role serotonergic agonist (CHEBI:35941)
ulotaront (CHEBI:228346) has role trace amine-associated receptor 1 agonist (CHEBI:228347)
ulotaront (CHEBI:228346) is a secondary amino compound (CHEBI:50995)
ulotaront (CHEBI:228346) is a thienopyran (CHEBI:48910)
IUPAC Name
1-[(7S)-4,7-dihydro-5H-thieno[2,3-c]pyran-7-yl]-N-methylmethanamine
INNs Sources
ulotaront WHO MedNet
ulotaront WHO MedNet
ulotaront WHO MedNet
ulotarontum WHO MedNet
Synonyms Sources
SEP 363856 ChEBI
SEP-363856 DrugBank
SEP-856 DrugBank
SEP363856 DrugBank
Manual Xrefs Databases
D12474 KEGG DRUG
DB15665 DrugBank
Ulotaront Wikipedia
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Citations Waiting for Citations Types Sources
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Last Modified
22 December 2023