CHEBI:229646 - gepirone hydrochloride

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ChEBI Name gepirone hydrochloride
ChEBI ID CHEBI:229646
Definition The hydrochloride salt of gepirone. It is a prescription medicine used to treat adults with a certain type of depression called major depressive disorder.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C19H29N5O2.ClH
Net Charge 0
Average Mass 395.930
Monoisotopic Mass 395.20880
InChI InChI=1S/C19H29N5O2.ClH/c1-19(2)14-16(25)24(17(26)15-19)9-4-3-8-22-10-12-23(13-11-22)18-20-6-5-7-21-18;/h5-7H,3-4,8-15H2,1-2H3;1H
InChIKey DGOCVISYYYQFEP-UHFFFAOYSA-N
SMILES Cl.CC1(C)CC(=O)N(CCCCN2CCN(CC2)C2=NC=CC=N2)C(=O)C1
Roles Classification
Biological Role(s): serotonergic agonist
An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.
Application(s): antidepressant
Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
serotonergic agonist
An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.
anxiolytic drug
Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing gepirone hydrochloride (CHEBI:229646) has part gepirone(1+) (CHEBI:229647)
gepirone hydrochloride (CHEBI:229646) has role antidepressant (CHEBI:35469)
gepirone hydrochloride (CHEBI:229646) has role anxiolytic drug (CHEBI:35474)
gepirone hydrochloride (CHEBI:229646) has role serotonergic agonist (CHEBI:35941)
gepirone hydrochloride (CHEBI:229646) is a hydrochloride (CHEBI:36807)
IUPAC Name
4,4-dimethyl-1-{4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl}piperidine-2,6-dione hydrochloride
Synonyms Sources
1-[4-(4,4-dimethyl-2,6-dioxopiperidin-1-yl)butyl]-4-(pyrimidin-2-yl)piperazin-1-ium chloride IUPAC
4,4-dimethyl-1-{4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl}piperidine-2,6-dione—hydrogen chloride IUPAC
BMY 13805 ChEBI
BMY 13805-1 ChEBI
BMY-13805 ChEBI
gepirone ER ChEBI
gepirone HCl ChEBI
MJ 13805 ChEBI
MJ-13805 ChEBI
Org 33062 ChEBI
Brand Name Source
Exxua KEGG DRUG
Manual Xrefs Databases
D04314 KEGG DRUG
DBSALT002148 DrugBank
EP1343504 Patent
View more database links
Registry Number Type Source
83928-66-9 CAS Registry Number DrugBank
Citations Waiting for Citations Types Sources
15323591 PubMed citation Europe PMC
15643103 PubMed citation Europe PMC
1981261 PubMed citation Europe PMC
24944406 PubMed citation Europe PMC
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2874469 PubMed citation Europe PMC
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31347611 PubMed citation Europe PMC
38079093 PubMed citation Europe PMC
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6140299 PubMed citation Europe PMC
8103528 PubMed citation Europe PMC
Last Modified
19 February 2024