amrinone (CHEBI:2686)

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ChEBI Name	amrinone

ChEBI ID	CHEBI:2686

Definition	A 3,4'-bipyridine substituted at positions 5 and 6 by an amino group and a keto function respectively. A pyridine phosphodiesterase 3 inhibitor, it is a drug that may improve the prognosis in patients with congestive heart failure.

Stars	This entity has been manually annotated by the ChEBI Team.

Secondary ChEBI IDs	CHEBI:95269

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Formula

C10H9N3O

Net Charge

Average Mass

187.198

Monoisotopic Mass

187.07456

InChI

InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14)

InChIKey

RNLQIBCLLYYYFJ-UHFFFAOYSA-N

SMILES

C1=CN=CC=C1C2=CNC(=O)C(=C2)N

Roles Classification
Biological Role(s):	EC 3.1.4.* (phosphoric diester hydrolase) inhibitor An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a phosphoric diester hydrolase (EC 3.1.4.*).

ChEBI Ontology
Outgoing	amrinone (CHEBI:2686) has role EC 3.1.4.* (phosphoric diester hydrolase) inhibitor (CHEBI:50218) amrinone (CHEBI:2686) is a bipyridines (CHEBI:50511)

IUPAC Name

5-amino[3,4'-bipyridin]-6(1H)-one

INN	Source
amrinone	ChemIDplus

Last Modified

05 March 2020