CHEBI:28509 - chloroethene

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ChEBI Name chloroethene
ChEBI ID CHEBI:28509
Definition A monohaloethene that is ethene in which one of the hydrogens has been replaced by a chloro group.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:9990, CHEBI:27293
Supplier Information eMolecules:29543396, ZINC000001887263
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Lisofylline (LSF) is a synthetic small molecule with novel anti-inflammatory properties. LSF can effectively prevent type 1 diabetes in preclinical models and improves the function and viability of isolated or transplanted pancreatic islets. It is a metabolite of pentoxifylline. As well, LSF improves cellular mitochondrial function and blocks interleukin-12 (IL-12) signaling and STAT-4 activation in target cells and tissues. IL-12 and STAT-4 activation are important pathways linked to inflammation and autoimmune damage to insulin producing cells. Therefore, LSF and related analogs could provide a new therapeutic approach to prevent or reverse type 1 diabetes. LSF also directly reduces glucose-induced changes in human kidney cells suggesting that LSF and analogs have the potential to treat the complications associated with diabetes.
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Formula C2H3Cl
Net Charge 0
Average Mass 62.49792
Monoisotopic Mass 61.99233
InChI InChI=1S/C2H3Cl/c1-2-3/h2H,1H2
InChIKey BZHJMEDXRYGGRV-UHFFFAOYSA-N
SMILES ClC=C
Roles Classification
Biological Role(s): carcinogenic agent
A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities.
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ChEBI Ontology
Outgoing chloroethene (CHEBI:28509) has role carcinogenic agent (CHEBI:50903)
chloroethene (CHEBI:28509) is a chloroethenes (CHEBI:23142)
chloroethene (CHEBI:28509) is a gas molecular entity (CHEBI:138675)
chloroethene (CHEBI:28509) is a monohaloethene (CHEBI:51313)
IUPAC Name
chloroethene
Synonyms Sources
chloroethene UniProt
Chloroethylene KEGG COMPOUND
chlorure de vinyle ChemIDplus
cloroetileno ChEBI
cloruro de vinilo ChEBI
ethylene monochloride ChemIDplus
monochloroethene ChemIDplus
monochloroethylene ChemIDplus
monovinyl chloride ChemIDplus
VC UM-BBD
Vinyl chloride KEGG COMPOUND
Vinylchlorid ChemIDplus
Manual Xrefs Databases
c0358 UM-BBD
C06793 KEGG COMPOUND
Chloroethene Wikipedia
View more database links
Registry Numbers Types Sources
100541 Gmelin Registry Number Gmelin
1731576 Reaxys Registry Number Reaxys
75-01-4 CAS Registry Number KEGG COMPOUND
75-01-4 CAS Registry Number NIST Chemistry WebBook
75-01-4 CAS Registry Number ChemIDplus
Citations Types Sources
15989139 PubMed citation Europe PMC
18678006 PubMed citation Europe PMC
Last Modified
19 July 2021