bendazac (CHEBI:31257)

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ChEBI Name	bendazac

ChEBI ID	CHEBI:31257

Definition	A monocarboxylic acid that is glycolic acid in which the hydrogen attached to the 2-hydroxy group is replaced by a 1-benzyl-1H-indazol-3-yl group. Although it has anti-inflammatory, antinecrotic, choleretic and antilipidaemic properties and has been used for the treatment of various inflammatory skin disorders, its principal effect is to inhibit the denaturation of proteins. Its lysine salt is used in the management of cataracts.

Stars	This entity has been manually annotated by the ChEBI Team.

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Formula

C16H14N2O3

Net Charge

Average Mass

282.29400

Monoisotopic Mass

282.10044

InChI

InChI=1S/C16H14N2O3/c19-15(20)11-21-16-13-8-4-5-9-14(13)18(17-16)10-12-6-2-1-3-7-12/h1-9H,10-11H2,(H,19,20)

InChIKey

BYFMCKSPFYVMOU-UHFFFAOYSA-N

SMILES

OC(=O)COc1nn(Cc2ccccc2)c2ccccc12

Roles Classification
Chemical Role(s):	radical scavenger A role played by a substance that can react readily with, and thereby eliminate, radicals. Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Bronsted base). (via oxoacid )

Application(s):	non-steroidal anti-inflammatory drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.

ChEBI Ontology
Outgoing	bendazac (CHEBI:31257) has role non-steroidal anti-inflammatory drug (CHEBI:35475) bendazac (CHEBI:31257) has role radical scavenger (CHEBI:48578) bendazac (CHEBI:31257) is a indazoles (CHEBI:38769) bendazac (CHEBI:31257) is a monocarboxylic acid (CHEBI:25384)

IUPAC Name

[(1-benzyl-1H-indazol-3-yl)oxy]acetic acid

Brand Name	Source
Iwazac	KEGG DRUG

Last Modified

22 February 2017