CHEBI:31303 - bromhexine hydrochloride

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ChEBI Name bromhexine hydrochloride
ChEBI ID CHEBI:31303
Definition A hydrochloride resulting from the reaction of equimolar amounts of bromhexine and hydrogen chloride. It is used as a mucolytic for the treatment of respiratory disorders associated with productive cough (i.e. a cough characterised by the production of sputum).
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information ChemicalBook:CB3249453, ChemicalBook:CB92617054, eMolecules:631787, Selleckchem:bromhexine-hydrochloride
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Formula C14H21Br2ClN2
Net Charge 0
Average Mass 412.59100
Monoisotopic Mass 409.97600
InChI InChI=1S/C14H20Br2N2.ClH/c1-18(12-5-3-2-4-6-12)9-10-7-11(15)8-13(16)14(10)17;/h7-8,12H,2-6,9,17H2,1H3;1H
InChIKey UCDKONUHZNTQPY-UHFFFAOYSA-N
SMILES Cl.CN(Cc1cc(Br)cc(Br)c1N)C1CCCCC1
Roles Classification
Application(s): mucolytic
A compound that alters the structure of mucus so as to decrease its viscosity and thereby facilitate its removal by ciliary action and expectoration. Compare with antitussives, which suppress the cough reflex, and expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing.
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ChEBI Ontology
Outgoing bromhexine hydrochloride (CHEBI:31303) has part bromhexine(1+) (CHEBI:77040)
bromhexine hydrochloride (CHEBI:31303) has role mucolytic (CHEBI:77034)
bromhexine hydrochloride (CHEBI:31303) is a hydrochloride (CHEBI:36807)
IUPAC Name
2,4-dibromo-6-{[cyclohexyl(methyl)amino]methyl}aniline hydrochloride
Synonyms Sources
2-amino-N-cyclohexyl-3,5-dibromo-N-methylbenzylamine hydrochloride ChemIDplus
3,5-dibromo-Nα-cyclohexyl-Nα-methyltoluene-α,2-diamine monohydrochloride ChemIDplus
bromhexine chloride ChemIDplus
bromhexine HCl ChemIDplus
bromohexine monohydrochloride ChemIDplus
N-(2-amino-3,5-dibromobenzyl)-N-methyl-cyclohexylammonium chloride ChemIDplus
N-(2-amino-3,5-dibromobenzyl)-N-methylcyclohexanaminium chloride IUPAC
N-cyclohexyl-N-methyl-(2-amino-3,5-dibromobenzyl)ammonium chloride ChemIDplus
Brand Names Sources
Auxit ChemIDplus
Broncokin ChemIDplus
Ophtolsol ChEBI
Quentan ChEBI
Viscolyt ChemIDplus
Manual Xrefs Databases
1786 VSDB
CN101817754 Patent
D01778 KEGG DRUG
View more database links
Registry Numbers Types Sources
4848376 Reaxys Registry Number Reaxys
611-75-6 CAS Registry Number ChemIDplus
Citations Types Sources
16385235 PubMed citation Europe PMC
2365032 PubMed citation Europe PMC
9260207 PubMed citation Europe PMC
Last Modified
21 January 2014