CHEBI:31347 - camostat mesylate

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ChEBI Name camostat mesylate
ChEBI ID CHEBI:31347
Definition A methanesulfonate (mesylate) salt prepared from equimolar amounts of camostat and methanesulfonic acid. It is a serine protease inhibitor approved and marketed in Japan in 1985 for the alleviation of acute symptoms associated with chronic pancreatitis. In 1994, it was approved for the treatment of postoperative reflux esophagitis.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information ChemicalBook:CB8299877, eMolecules:3714605, Selleckchem:camostat-mesilate-foy-305
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Formula C20H22N4O5.CH4O3S
Net Charge 0
Average Mass 494.520
Monoisotopic Mass 494.14713
InChI InChI=1S/C20H22N4O5.CH4O3S/c1-24(2)17(25)12-28-18(26)11-13-3-9-16(10-4-13)29-19(27)14-5-7-15(8-6-14)23-20(21)22;1-5(2,3)4/h3-10H,11-12H2,1-2H3,(H4,21,22,23);1H3,(H,2,3,4)
InChIKey FSEKIHNIDBATFG-UHFFFAOYSA-N
SMILES CS(O)(=O)=O.CN(C)C(=O)COC(=O)CC1=CC=C(OC(=O)C2=CC=C(NC(N)=N)C=C2)C=C1
Roles Classification
Biological Role(s): anticoronaviral agent
Any antiviral agent which inhibits the activity of coronaviruses.
antiviral agent
A substance that destroys or inhibits replication of viruses.
serine protease inhibitor
Any protease inhibitor that restricts the action of a serine protease.
Application(s): anti-inflammatory agent
Any compound that has anti-inflammatory effects.
antifibrinolytic drug
A drug that prevent fibrinolysis or lysis of a blood clot or thrombus.
antihypertensive agent
Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing camostat mesylate (CHEBI:31347) has part camostat(1+) (CHEBI:169939)
camostat mesylate (CHEBI:31347) has role anti-inflammatory agent (CHEBI:67079)
camostat mesylate (CHEBI:31347) has role anticoronaviral agent (CHEBI:149553)
camostat mesylate (CHEBI:31347) has role antifibrinolytic drug (CHEBI:48675)
camostat mesylate (CHEBI:31347) has role antihypertensive agent (CHEBI:35674)
camostat mesylate (CHEBI:31347) has role antineoplastic agent (CHEBI:35610)
camostat mesylate (CHEBI:31347) has role antiviral agent (CHEBI:22587)
camostat mesylate (CHEBI:31347) has role serine protease inhibitor (CHEBI:64926)
camostat mesylate (CHEBI:31347) is a methanesulfonate salt (CHEBI:38037)
IUPAC Name
4-{2-[2-(dimethylamino)-2-oxoethoxy]-2-oxoethyl}phenyl 4-carbamimidamidobenzoate methanesulfonate
Synonyms Sources
amino{4-[(4-{2-[2-(dimethylamino)-2-oxoethoxy]-2-oxoethyl}phenoxy)carbonyl]anilino}methaniminium methanesulfonate IUPAC
camostat mesilate ChemIDplus
camostat methanesulfonate ChEBI
camostat monomethanesulfonate ChemIDplus
N,N-dimethylcarbamoylmethyl 4-(4-guanidinobenzoyloxy)phenylacetate methanesulfate ChemIDplus
Brand Names Sources
Foipan ChemIDplus
Foistar ChEBI
FOY 305 ChemIDplus
FOY-305 ChEBI
FOY305 ChEBI
Manual Xrefs Databases
39251 ChemSpider
D01766 KEGG DRUG
DBSALT002914 DrugBank
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Registry Number Type Source
59721-29-8 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
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Last Modified
13 April 2021