CHEBI:31460 - desferrioxamine B mesylate

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name desferrioxamine B mesylate
ChEBI ID CHEBI:31460
Definition A methanesulfonate salt obtained by reaction of desferrioxamine B with one molar equivalent of methanesulfonic acid. It is an iron-chelating medicine used to remove excess iron from the body. It binds to iron in the blood, which is then passed out in the urine.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information ChemicalBook:CB4372020, eMolecules:537789
Download Molfile XML SDF
Formulae C25H48N6O8.CH4SO3
C26H52N6SO11
Net Charge 0
Average Mass 656.79092
Monoisotopic Mass 656.34148
InChI InChI=1S/C25H48N6O8.CH4O3S/c1-21(32)29(37)18-9-3-6-16-27-22(33)12-14-25(36)31(39)20-10-4-7-17-28-23(34)11-13-24(35)30(38)19-8-2-5-15-26;1-5(2,3)4/h37-39H,2-20,26H2,1H3,(H,27,33)(H,28,34);1H3,(H,2,3,4)
InChIKey IDDIJAWJANBQLJ-UHFFFAOYSA-N
SMILES [H+].CS([O-])(=O)=O.CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN
Roles Classification
Chemical Role(s): iron chelator

Biological Role(s): ferroptosis inhibitor
Any substance that inhibits the process of ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms.
Application(s): antidote
Any protective agent counteracting or neutralizing the action of poisons.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing desferrioxamine B mesylate (CHEBI:31460) has part desferrioxamine B (CHEBI:4356)
desferrioxamine B mesylate (CHEBI:31460) has role antidote (CHEBI:50247)
desferrioxamine B mesylate (CHEBI:31460) has role ferroptosis inhibitor (CHEBI:173084)
desferrioxamine B mesylate (CHEBI:31460) has role iron chelator (CHEBI:38157)
desferrioxamine B mesylate (CHEBI:31460) is a methanesulfonate salt (CHEBI:38037)
IUPAC Name
N'-{5-[acetyl(hydroxy)amino]pentyl}-N-(5-{4-[(5-aminopentyl)(hydroxy)amino]-4-oxobutanamido}pentyl)-N-hydroxybutanediamide methanesulfonate
Synonyms Sources
Deferoxamine B mesylate ChemIDplus
Deferoxamine mesylate ChemIDplus
Deferoxamine methanesulfonate ChemIDplus
desferrioxamine B methanesulfonate ChemIDplus
desferrioxamine mesilate DrugBank
Desferrioxamine mesylate ChemIDplus
Desferrioxamine methanesulfonate ChemIDplus
Brand Names Sources
Desferal DrugBank
Desferin DrugBank
Manual Xrefs Databases
CPD-8951 MetaCyc
D01186 KEGG DRUG
DBSALT000964 DrugBank
View more database links
Registry Numbers Types Sources
138-14-7 CAS Registry Number ChemIDplus
6047788 Beilstein Registry Number Beilstein
Citations Waiting for Citations
Last Modified
27 May 2021