CHEBI:32004 - pipamperone dihydrochloride

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ChEBI Name pipamperone dihydrochloride
ChEBI ID CHEBI:32004
Definition A hydrochloride resulting from the reaction of pipamperone with 2 mol eq. of hydrogen chloride. It is used as an antipsychotic.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:78944
Supplier Information
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Formula C21H32Cl2FN3O2
Net Charge 0
Average Mass 448.40200
Monoisotopic Mass 447.18556
InChI InChI=1S/C21H30FN3O2.2ClH/c22-18-8-6-17(7-9-18)19(26)5-4-12-24-15-10-21(11-16-24,20(23)27)25-13-2-1-3-14-25;;/h6-9H,1-5,10-16H2,(H2,23,27);2*1H
InChIKey BMXXSXQVMCXGJM-UHFFFAOYSA-N
SMILES Cl.Cl.NC(=O)C1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)N1CCCCC1
Roles Classification
Biological Role(s): dopaminergic antagonist
A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
serotonergic antagonist
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
Application(s): dopaminergic antagonist
A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
first generation antipsychotic
Antipsychotic drugs which can have different modes of action but which tend to be more likely than second generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements; such body movements can become permanent even after treatment has ceased.
serotonergic antagonist
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing pipamperone dihydrochloride (CHEBI:32004) has part pipamperone(2+) (CHEBI:78943)
pipamperone dihydrochloride (CHEBI:32004) has role dopaminergic antagonist (CHEBI:48561)
pipamperone dihydrochloride (CHEBI:32004) has role first generation antipsychotic (CHEBI:65190)
pipamperone dihydrochloride (CHEBI:32004) has role serotonergic antagonist (CHEBI:48279)
pipamperone dihydrochloride (CHEBI:32004) is a hydrochloride (CHEBI:36807)
IUPAC Name
1'-[4-(4-fluorophenyl)-4-oxobutyl]-1,4'-bipiperidine-4'-carboxamide dihydrochloride
Synonyms Sources
1'-(3-(p-fluorobenzoyl)propyl)-(1,4'-bipiperidine)-4'-carboxamide dihydrochloride ChEBI
4'-carbamoyl-1'-[4-(4-fluorophenyl)-4-oxobutyl]-1,4'-bipiperidinium dichloride IUPAC
p-fluoro-γ-(4-piperidino-4-carbamoylpiperidino)butyrophenone dihydrochloride ChEBI
pipamperone hydrochloride KEGG DRUG
Brand Names Sources
Dipiperon ChEBI
Piperonil ChEBI
Propitan ChemIDplus
Manual Xref Database
D01482 KEGG DRUG
View more database links
Registry Numbers Types Sources
2448-68-2 CAS Registry Number KEGG DRUG
2448-68-2 CAS Registry Number ChemIDplus
9174635 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
1020694 PubMed citation Europe PMC
354326 PubMed citation Europe PMC
970185 PubMed citation Europe PMC
Last Modified
24 June 2014