CHEBI:3207 - budesonide

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ChEBI Name budesonide
ChEBI ID CHEBI:3207
Definition A glucocorticoid steroid having a highly oxygenated pregna-1,4-diene structure. It is used mainly in the treatment of asthma and non-infectious rhinitis and for treatment and prevention of nasal polyposis.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C25H34O6
Net Charge 0
Average Mass 430.53386
Monoisotopic Mass 430.23554
InChI InChI=1S/C25H34O6/c1-4-5-21-30-20-11-17-16-7-6-14-10-15(27)8-9-23(14,2)22(16)18(28)12-24(17,3)25(20,31-21)19(29)13-26/h8-10,16-18,20-22,26,28H,4-7,11-13H2,1-3H3/t16-,17-,18-,20+,21?,22+,23-,24-,25+/m0/s1
InChIKey VOVIALXJUBGFJZ-KWVAZRHASA-N
SMILES [H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]1(C)[C@@]2([H])C[C@H]2OC(CCC)O[C@@]12C(=O)CO
Roles Classification
Biological Role(s): drug allergen
Any drug which causes the onset of an allergic reaction.
hormone
Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds.
(via steroid hormone )
Application(s): bronchodilator agent
An agent that causes an increase in the expansion of a bronchus or bronchial tubes.
anti-inflammatory drug
A substance that reduces or suppresses inflammation.
drug allergen
Any drug which causes the onset of an allergic reaction.
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ChEBI Ontology
Outgoing budesonide (CHEBI:3207) has parent hydride pregnane (CHEBI:8386)
budesonide (CHEBI:3207) has role anti-inflammatory drug (CHEBI:35472)
budesonide (CHEBI:3207) has role bronchodilator agent (CHEBI:35523)
budesonide (CHEBI:3207) has role drug allergen (CHEBI:88188)
budesonide (CHEBI:3207) is a 11β-hydroxy steroid (CHEBI:35346)
budesonide (CHEBI:3207) is a 20-oxo steroid (CHEBI:36885)
budesonide (CHEBI:3207) is a 21-hydroxy steroid (CHEBI:35344)
budesonide (CHEBI:3207) is a 3-oxo-Δ1,Δ4-steroid (CHEBI:77166)
budesonide (CHEBI:3207) is a cyclic acetal (CHEBI:59770)
budesonide (CHEBI:3207) is a glucocorticoid (CHEBI:24261)
budesonide (CHEBI:3207) is a primary α-hydroxy ketone (CHEBI:139590)
IUPAC Name
11β,21-dihydroxy-16α,17α-(butane-1,1-diyldioxy)pregna-1,4-diene-3,20-dione
INN Source
budesonide KEGG DRUG
Synonym Source
(11β,16α)-16,17-(Butylidenebis(oxy))-11,21-dihydroxypregna-1,4-diene-3,20-dione ChemIDplus
Manual Xrefs Databases
419 DrugCentral
Budesonide Wikipedia
D00246 KEGG DRUG
DB01222 DrugBank
DE2323215 Patent
US3929768 Patent
View more database links
Registry Numbers Types Sources
51333-22-3 CAS Registry Number KEGG DRUG
51333-22-3 CAS Registry Number ChemIDplus
Citation Waiting for Citations Type Source
21616561 PubMed citation Europe PMC
Last Modified
07 March 2019