CHEBI:32270 - trospium chloride

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ChEBI Name trospium chloride
ChEBI ID CHEBI:32270
Definition An organic chloride salt of trospium. It is an antispasmodic drug used for the treatment of overactive bladder.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C25H30NO3.Cl
Net Charge 0
Average Mass 427.970
Monoisotopic Mass 427.19142
InChI InChI=1S/C25H30NO3.ClH/c27-24(25(28,19-9-3-1-4-10-19)20-11-5-2-6-12-20)29-23-17-21-13-14-22(18-23)26(21)15-7-8-16-26;/h1-6,9-12,21-23,28H,7-8,13-18H2;1H/q+1;/p-1/t21-,22+,23+;
InChIKey RVCSYOQWLPPAOA-QKYUOBHYSA-M
SMILES [N+]12([C@]3(C[C@H](OC(C(C4=CC=CC=C4)(C5=CC=CC=C5)O)=O)C[C@@]1(CC3)[H])[H])CCCC2.[Cl-]
Roles Classification
Biological Role(s): muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
Application(s): antispasmodic drug
A drug that suppresses spasms. These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder.
muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
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ChEBI Ontology
Outgoing trospium chloride (CHEBI:32270) has part trospium (CHEBI:145791)
trospium chloride (CHEBI:32270) has role antispasmodic drug (CHEBI:53784)
trospium chloride (CHEBI:32270) has role muscarinic antagonist (CHEBI:48876)
trospium chloride (CHEBI:32270) is a organic chloride salt (CHEBI:36094)
trospium chloride (CHEBI:32270) is a quaternary ammonium salt (CHEBI:35273)
IUPAC Name
(1S,3R,5R)-3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-8λ5-azaspiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-8-ylium chloride
INNs Sources
chlorure de trospium WHO MedNet
cloruro de trospio WHO MedNet
trospii chloridum WHO MedNet
trospium chloride WHO MedNet
Synonyms Sources
IP-631 ChEBI
IP631 ChemIDplus
Trospium chloride KEGG DRUG
trospium Cl ChemIDplus
Brand Names Sources
Regurin ChEBI
Relaspium ChemIDplus
Sanctura ChemIDplus
Sanctura XR ChemIDplus
Santura ChemIDplus
Spasmed ChEBI
Spasmex KEGG DRUG
Spasmo 3 ChemIDplus
Spasmo-lyt ChemIDplus
Spasmolyt ChEBI
Spasmoplex KEGG DRUG
Trofame ChEBI
Trosec DrugBank
Trospikan ChEBI
Uraplex ChemIDplus
Manual Xrefs Databases
2776 DrugCentral
D01103 KEGG DRUG
DBSALT000883 DrugBank
Trospium_chloride Wikipedia
View more database links
Registry Number Type Source
10405-02-4 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
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Last Modified
17 January 2020