CHEBI:331697 - atomoxetine hydrochloride

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ChEBI Name atomoxetine hydrochloride
ChEBI ID CHEBI:331697
Definition The hydrochloride salt of atomoxetine.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C17H22ClNO
Net Charge 0
Average Mass 291.81600
Monoisotopic Mass 291.13899
InChI InChI=1S/C17H21NO.ClH/c1-14-8-6-7-11-16(14)19-17(12-13-18-2)15-9-4-3-5-10-15;/h3-11,17-18H,12-13H2,1-2H3;1H/t17-;/m1./s1
InChIKey LUCXVPAZUDVVBT-UNTBIKODSA-N
SMILES Cl.CNCC[C@@H](Oc1ccccc1C)c1ccccc1
Roles Classification
Biological Role(s): adrenergic uptake inhibitor
Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.
Application(s): antidepressant
Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
adrenergic uptake inhibitor
Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing atomoxetine hydrochloride (CHEBI:331697) has part atomoxetine (CHEBI:127342)
atomoxetine hydrochloride (CHEBI:331697) has role adrenergic uptake inhibitor (CHEBI:35640)
atomoxetine hydrochloride (CHEBI:331697) has role antidepressant (CHEBI:35469)
atomoxetine hydrochloride (CHEBI:331697) is a hydrochloride (CHEBI:36807)
IUPAC Name
(3R)-N-methyl-3-(2-methylphenoxy)-3-phenylpropan-1-amine hydrochloride
INNs Sources
atomoxetine ChEBI
tomoxetine DrugBank
Synonyms Sources
(-)-N-Methyl-3-phenyl-3-(o-tolyloxy)propylamine hydrochloride ChemIDplus
(R)-(-)-Tomoxetine hydrochloride ChemIDplus
(R)-Tomoxetine hydrochloride ChemIDplus
Atomoxetine HCl ChemIDplus
Tomoxetine hydrochloride KEGG DRUG
Manual Xrefs Databases
D02574 KEGG DRUG
DB00289 DrugBank
View more database links
Registry Numbers Types Sources
5318974 Beilstein Registry Number Beilstein
82248-59-7 CAS Registry Number DrugBank
82248-59-7 CAS Registry Number ChemIDplus
82248-59-7 CAS Registry Number KEGG DRUG
Last Modified
11 January 2010