CHEBI:36382 - (2R,3S,11bS)-benzquinamide

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ChEBI Name (2R,3S,11bS)-benzquinamide
ChEBI ID CHEBI:36382
ChEBI ASCII Name (2R,3S,11bS)-benzquinamide
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C22H32N2O5
Net Charge 0
Average Mass 404.49996
Monoisotopic Mass 404.23112
InChI InChI=1S/C22H32N2O5/c1-6-23(7-2)22(26)17-13-24-9-8-15-10-20(27-4)21(28-5)11-16(15)18(24)12-19(17)29-14(3)25/h10-11,17-19H,6-9,12-13H2,1-5H3/t17-,18-,19+/m0/s1
InChIKey JSZILQVIPPROJI-GBESFXJTSA-N
SMILES [H][C@@]12C[C@@H](OC(C)=O)[C@H](CN1CCc1cc(OC)c(OC)cc21)C(=O)N(CC)CC
Roles Classification
Biological Role(s): H1-receptor antagonist
H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
(via benzquinamide )
muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
(via benzquinamide )
Application(s): antiemetic
A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors.
(via benzquinamide )
sedative
A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
(via benzquinamide )
H1-receptor antagonist
H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
(via benzquinamide )
muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
(via benzquinamide )
antipsychotic agent
Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
(via benzquinamide )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing (2R,3S,11bS)-benzquinamide (CHEBI:36382) is a benzquinamide (CHEBI:27662)
IUPAC Name
(2R,3S,11bS)-3-(diethylcarbamoyl)-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl acetate
Registry Number Type Source
502387 Beilstein Registry Number Beilstein
Last Modified
21 August 2006