clofibrate (CHEBI:3750)

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ChEBI Name	clofibrate

ChEBI ID	CHEBI:3750

Definition	The ethyl ester of clofibric acid.

Stars	This entity has been manually annotated by the ChEBI Team.

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Formula

C12H15ClO3

Net Charge

Average Mass

242.69900

Monoisotopic Mass

242.07097

InChI

InChI=1S/C12H15ClO3/c1-4-15-11(14)12(2,3)16-10-7-5-9(13)6-8-10/h5-8H,4H2,1-3H3

InChIKey

KNHUKKLJHYUCFP-UHFFFAOYSA-N

SMILES

CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1

Roles Classification
Biological Role(s):	PPARalpha agonist A PPAR modulator which activates the peroxisome proliferator-activated receptor-alpha.

Application(s):	anticholesteremic drug A substance used to lower plasma cholesterol levels. antilipemic drug A substance used to treat hyperlipidemia (an excess of lipids in the blood). geroprotector Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.

ChEBI Ontology
Outgoing	clofibrate (CHEBI:3750) has functional parent clofibric acid (CHEBI:34648) clofibrate (CHEBI:3750) has role anticholesteremic drug (CHEBI:35821) clofibrate (CHEBI:3750) has role antilipemic drug (CHEBI:35679) clofibrate (CHEBI:3750) has role geroprotector (CHEBI:176497) clofibrate (CHEBI:3750) has role PPARα agonist (CHEBI:70782) clofibrate (CHEBI:3750) is a aromatic ether (CHEBI:35618) clofibrate (CHEBI:3750) is a ethyl ester (CHEBI:23990) clofibrate (CHEBI:3750) is a monochlorobenzenes (CHEBI:83403)

IUPAC Name

ethyl 2-(4-chlorophenoxy)-2-methylpropanoate

Synonyms	Sources
2-(4-Chlorophenoxy)-2-methylpropanoic acid ethyl ester	ChemIDplus
2-(p-Chlorophenoxy)-2-methylpropionic acid ethyl ester	ChemIDplus
alpha-(p-Chlorophenoxy)isobutyric acid, ethyl ester	ChemIDplus
alpha-p-Chlorophenoxyisobutyryl ethyl ester	ChemIDplus
Clofibrate	KEGG COMPOUND
EPIB	DrugBank
Ethyl 2-(p-chlorophenoxy)isobutyrate	ChemIDplus
Ethyl chlorophenoxyisobutyrate	ChemIDplus
Ethyl clofibrate	ChemIDplus
Liprin	ChemIDplus

Last Modified

20 September 2021