fluorescein 5-isothiocyanate (CHEBI:37918)

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ChEBI Name	fluorescein 5-isothiocyanate

ChEBI ID	CHEBI:37918

Definition	The 5-isomer of fluorescein isothiocyanate. Acts as a fluorescent probe capable of being conjugated to tissue and proteins; used as a label in fluorescent antibody staining procedures as well as protein- and amino acid-binding techniques.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formula

C21H11NO5S

Net Charge

Average Mass

389.38178

Monoisotopic Mass

389.03579

InChI

InChI=1S/C21H11NO5S/c23-12-2-5-16-18(8-12)26-19-9-13(24)3-6-17(19)21(16)15-4-1-11(22-10-28)7-14(15)20(25)27-21/h1-9,23-24H

InChIKey

MHMNJMPURVTYEJ-UHFFFAOYSA-N

SMILES

Oc1ccc2c(Oc3cc(O)ccc3C22OC(=O)c3cc(ccc23)N=C=S)c1

Roles Classification
Biological Role(s):	hapten Any substance capable of eliciting an immune response only when attached to a large carrier such as a protein. Examples include dinitrophenols; oligosaccharides; peptides; and heavy metals. (via fluorescein isothiocyanate ) antigen Any substance that stimulates an immune response in the body, such as through antibody production or by presentation to a T-cell receptor after binding to a major histocompability complex (MHC). (via fluorescein isothiocyanate )

Application(s):	fluorochrome A fluorescent dye used to stain biological specimens. (via fluorescein isothiocyanate ) fluorescent dye (via fluorescein isothiocyanate ) fluorescent probe A role played by a fluorescent molecular entity used to study the microscopic environment by fluorescence spectroscopy. (via fluorescein isothiocyanate )

ChEBI Ontology
Outgoing	fluorescein 5-isothiocyanate (CHEBI:37918) is a fluorescein isothiocyanate (CHEBI:37926)

IUPAC Name

3',6'-dihydroxy-5-isothiocyanato-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one

Synonyms	Sources
2-(6-Hydroxy-3-oxo-(3H)-xanthen-9-yl)-5-isothiocyanatobenzoic acid	ChemIDplus
3',6'-dihydroxy-5-isothiocyanatospiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one	ChemIDplus
5-FITC	ChEBI
5-isothiocyanatofluorescein	ChEBI
F5ITC	ChEBI
FITC isomer 1	ChEBI
FITC-I	ChEBI
fluorescein isothiocyanate isomer 1	ChEBI
Fluorescein-5-isothiocyanat	ChEBI
fluorescein-5-isothiocyanate	ChemIDplus
Fluoreszein-5-isothiocyanat	ChEBI

Last Modified

03 November 2017