CHEBI:44245 - menaquinone-7

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ChEBI Name menaquinone-7
ChEBI ID CHEBI:44245
Definition A menaquinone whose side-chain contains seven isoprene units in an all-trans-configutation.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C46H64O2
Net Charge 0
Average Mass 648.99920
Monoisotopic Mass 648.49063
InChI InChI=1S/C46H64O2/c1-34(2)18-12-19-35(3)20-13-21-36(4)22-14-23-37(5)24-15-25-38(6)26-16-27-39(7)28-17-29-40(8)32-33-42-41(9)45(47)43-30-10-11-31-44(43)46(42)48/h10-11,18,20,22,24,26,28,30-32H,12-17,19,21,23,25,27,29,33H2,1-9H3/b35-20+,36-22+,37-24+,38-26+,39-28+,40-32+
InChIKey RAKQPZMEYJZGPI-LJWNYQGCSA-N
SMILES CC(C)=CCC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC1=C(C)C(=O)c2ccccc2C1=O
Metabolite of Species Details
Bacillus subtilis (NCBI:txid1423) See: PubMed
Mycoplasma genitalium (NCBI:txid2097) See: PubMed
Escherichia coli (NCBI:txid562) See: PubMed
Homo sapiens (NCBI:txid9606) See: PubMed
Homo sapiens (NCBI:txid9606) Found in blood serum (BTO:0000133). See: PubMed
Roles Classification
Biological Role(s): Escherichia coli metabolite
Any bacterial metabolite produced during a metabolic reaction in Escherichia coli.
(via menaquinone )
human blood serum metabolite
Any metabolite (endogenous or exogenous) found in human blood serum samples.
cofactor
An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group).
Mycoplasma genitalium metabolite
Any bacterial metabolite produced during a metabolic reaction in Mycoplasma genitalium.
mouse metabolite
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
(via vitamin K )
fat-soluble vitamin (role)
Any vitamin that dissolves in fats and are stored in body tissues. Unlike the water-soluble vitamins, they are stored in the body for long periods of time and generally pose a greater risk for toxicity when consumed in excess.
(via vitamin K )
Application(s): bone density conservation agent
An agent that inhibits bone resorption and/or favor bone mineralization and bone regeneration. Used to heal bone fractures and to treat bone diseases such as osteopenia and osteoporosis.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing menaquinone-7 (CHEBI:44245) has role Escherichia coli metabolite (CHEBI:76971)
menaquinone-7 (CHEBI:44245) has role Mycoplasma genitalium metabolite (CHEBI:131604)
menaquinone-7 (CHEBI:44245) has role bone density conservation agent (CHEBI:50646)
menaquinone-7 (CHEBI:44245) has role cofactor (CHEBI:23357)
menaquinone-7 (CHEBI:44245) has role human blood serum metabolite (CHEBI:85234)
menaquinone-7 (CHEBI:44245) is a menaquinone (CHEBI:16374)
IUPAC Name
2-[(2E,6E,10E,14E,18E,22E)-3,7,11,15,19,23,27-heptamethyloctacosa-2,6,10,14,18,22,26-heptaen-1-yl]-3-methylnaphthalene-1,4-dione
Synonyms Sources
(all-E)-2-(3,7,11,15,19,23,27-heptamethyl-2,6,10,14,18,22,26-octacosahept-aenyl)-3-methyl-1,4-naphthoquinone ChemIDplus
(all-E)-2-(3,7,11,15,19,23,27-heptamethyl-2,6,10,14,18,22,26-octacosaheptaenyl)-3-methyl-1,4-naphthalenedione ChemIDplus
menaquinone 7 ChEBI
menaquinone-7 UniProt
menaquinone-7 ChemIDplus
MK-7 ChEBI
vitamin K2(35) ChemIDplus
vitamin MK 7 ChemIDplus
Manual Xrefs Databases
CPD-9718 MetaCyc
DB13075 DrugBank
MQ7 PDBeChem
View more database links
Registry Numbers Types Sources
2124-57-4 CAS Registry Number ChemIDplus
2343160 Reaxys Registry Number Reaxys
2343160 Beilstein Registry Number Beilstein
Citations Waiting for Citations Types Sources
13946233 PubMed citation Europe PMC
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IND606538604 Agricola citation Europe PMC
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IND607052678 Agricola citation Europe PMC
Last Modified
26 July 2021