CHEBI:473992 - nystatin A1

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ChEBI Name nystatin A1
ChEBI ID CHEBI:473992
ChEBI ASCII Name nystatin A1
Definition A polyene macrolide antibiotic; part of the nystatin complex produced by several Streptomyces species. It is an antifungal antibiotic used for the treatment of topical fungal infections caused by a broad spectrum of fungal pathogens comprising yeast-like and filamentous species.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:31926
Supplier Information
Download Molfile XML SDF
Formula C47H75NO17
Net Charge 0
Average Mass 926.107
Monoisotopic Mass 925.50350
InChI InChI=1S/C47H75NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-36(53)35(52)20-19-31(49)21-32(50)22-33(51)23-39(55)62-29(3)28(2)42(27)56/h5-6,8,10-18,27-38,40-44,46,49-54,56-58,61H,7,9,19-26,48H2,1-4H3,(H,59,60)/b6-5+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28-,29-,30+,31+,32+,33+,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1
InChIKey VQOXZBDYSJBXMA-NQTDYLQESA-N
SMILES [H][C@]12C[C@@H](O[C@@H]3O[C@H](C)[C@@H](O)[C@H](N)[C@@H]3O)\C=C\C=C\C=C\C=C\CC\C=C\C=C\[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@](O)(C[C@H](O)[C@H]1C(O)=O)O2
Metabolite of Species Details
Streptomyces noursei (NCBI:txid1971) See: DOI
Streptomyces sp. HSG2 (NCBI:txid2797167) See: PubMed
Amycolatopsis aidingensis (NCBI:txid2842453) Species also known as Amycolatopsis sp. YIM 96748. See: PubMed
Streptomyces ahygroscopicus (NCBI:txid387846) See: PubMed
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): bacterial metabolite
Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
(via nystatins )
antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
(via macrolide antibiotic )
(via carbohydrate-containing antibiotic )
antifungal drug
Any antifungal agent used to prevent or treat fungal infections in humans or animals.
(via antibiotic antifungal drug )
antifungal agent
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
(via antibiotic antifungal agent )
Application(s): antifungal drug
Any antifungal agent used to prevent or treat fungal infections in humans or animals.
(via antibiotic antifungal drug )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing nystatin A1 (CHEBI:473992) is a nystatins (CHEBI:59676)
Incoming nystatin (CHEBI:7660) has part nystatin A1 (CHEBI:473992)
IUPAC Name
(1S,3R,4R,7R,9R,11R,15S,16R,17R,18S,19E,21E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(3-amino-3,6-dideoxy-β-D-mannopyranosyl)oxy]-1,3,4,7,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,25,27,29,31-hexaene-36-carboxylic acid
Synonym Source
nystatin A1 LIPID MAPS
Manual Xrefs Databases
2985 VSDB
C12155 KEGG COMPOUND
HMDB0242564 HMDB
LMPK06000004 LIPID MAPS
View more database links
Registry Numbers Types Sources
12153125 Beilstein Registry Number Beilstein
34786-70-4 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
1086913 PubMed citation Europe PMC
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Last Modified
18 August 2022