CHEBI:50781 - EC 1.3.1.22 [3-oxo-5α-steroid 4-dehydrogenase (NADP+)] inhibitor

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name EC 1.3.1.22 [3-oxo-5α-steroid 4-dehydrogenase (NADP+)] inhibitor
ChEBI ID CHEBI:50781
ChEBI ASCII Name EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor
Definition An EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of of 3-oxo-5α-steroid 4-dehydrogenase (NADP+), EC 1.3.1.22, the enzyme which converts testosterone (CHEBI:17347) into the more potent androgen 5α-dihydrotestosterone.
Stars This entity has been manually annotated by the ChEBI Team.
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ChEBI Ontology
Outgoing EC 1.3.1.22 [3-oxo-5α-steroid 4-dehydrogenase (NADP+)] inhibitor (CHEBI:50781) is a EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD+ or NADP+ as acceptor) inhibitor (CHEBI:76857)
Incoming 3',4',5-trihydroxy-3,7-dimethoxyflavone (CHEBI:18010) has role EC 1.3.1.22 [3-oxo-5α-steroid 4-dehydrogenase (NADP+)] inhibitor (CHEBI:50781)
3',4',7-trihydroxyisoflavone (CHEBI:50399) has role EC 1.3.1.22 [3-oxo-5α-steroid 4-dehydrogenase (NADP+)] inhibitor (CHEBI:50781)
4-pregnen-20,21-diol-3-one (CHEBI:87841) has role EC 1.3.1.22 [3-oxo-5α-steroid 4-dehydrogenase (NADP+)] inhibitor (CHEBI:50781)
dutasteride (CHEBI:521033) has role EC 1.3.1.22 [3-oxo-5α-steroid 4-dehydrogenase (NADP+)] inhibitor (CHEBI:50781)
finasteride (CHEBI:5062) has role EC 1.3.1.22 [3-oxo-5α-steroid 4-dehydrogenase (NADP+)] inhibitor (CHEBI:50781)
impatienol (CHEBI:72634) has role EC 1.3.1.22 [3-oxo-5α-steroid 4-dehydrogenase (NADP+)] inhibitor (CHEBI:50781)
prunetin (CHEBI:8600) has role EC 1.3.1.22 [3-oxo-5α-steroid 4-dehydrogenase (NADP+)] inhibitor (CHEBI:50781)
Synonyms Sources
3-oxo-5α-steroid 4-dehydrogenase (NADP+) (EC 1.3.1.22) inhibitor ChEBI
3-oxo-5α-steroid 4-dehydrogenase (NADP+) (EC 1.3.1.22) inhibitors ChEBI
3-oxo-5α-steroid 4-dehydrogenase (NADP+) inhibitor ChEBI
3-oxo-5α-steroid 4-dehydrogenase (NADP+) inhibitors ChEBI
3-oxo-5α-steroid 4-dehydrogenase inhibitor ChEBI
3-oxo-5α-steroid 4-dehydrogenase inhibitors ChEBI
3-oxo-5α-steroid:NADP+ Δ4-oxidoreductase inhibitor ChEBI
3-oxo-5α-steroid:NADP+ Δ4-oxidoreductase inhibitors ChEBI
3-oxosteroid 5α-reductase inhibitor ChEBI
3-oxosteroid Δ4-dehydrogenase inhibitor ChEBI
4-ene-3-oxosteroid 5α-reductase inhibitor ChEBI
4-ene-5α-reductase inhibitor ChEBI
5α-oxidoreductase inhibitor ChEBI
5α-oxidoreductase inhibitors ChEBI
5α-reductase inhibitor ChEBI
5α-reductase inhibitors ChEBI
cholest-4-en-3-one 5α-reductase inhibitor ChEBI
cholestenone 5α-reductase inhibitor ChEBI
cholestenone 5α-reductase inhibitors ChEBI
Δ4-3-ketosteroid 5α-oxidoreductase inhibitor ChEBI
Δ4-3-ketosteroid 5α-oxidoreductase inhibitors ChEBI
EC 1.3.1.22 (3-oxo-5α-steroid 4-dehydrogenase (NADP+)) inhibitor ChEBI
EC 1.3.1.22 (3-oxo-5α-steroid 4-dehydrogenase (NADP+)) inhibitors ChEBI
EC 1.3.1.22 [3-oxo-5α-steroid 4-dehydrogenase (NADP+)] inhibitors ChEBI
EC 1.3.1.22 inhibitor ChEBI
EC 1.3.1.22 inhibitors ChEBI
reduced nicotinamide adenine dinucleotide phosphate:Δ4-3-ketosteroid 5α-oxidoreductase inhibitor ChEBI
reduced nicotinamide adenine dinucleotide phosphate:Δ4-3-ketosteroid 5α-oxidoreductase inhibitors ChEBI
steroid 5α-hydrogenase inhibitor ChEBI
steroid 5α-hydrogenase inhibitors ChEBI
steroid 5α-reductase inhibitor ChEBI
steroid 5α-reductase inhibitors ChEBI
testosterone 5α-reductase inhibitor ChEBI
testosterone 5α-reductase inhibitors ChEBI
testosterone Δ4-5α-reductase inhibitor ChEBI
testosterone Δ4-5α-reductase inhibitors ChEBI
testosterone Δ4-hydrogenase inhibitor ChEBI
testosterone Δ4-hydrogenase inhibitors ChEBI
Manual Xref Database
5-alpha-reductase_inhibitor Wikipedia
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Last Modified
07 April 2016