flavoxate hydrochloride (CHEBI:5089)

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ChEBI Name	flavoxate hydrochloride

ChEBI ID	CHEBI:5089

Definition	The hydrochloride salt of flavoxate.

Stars	This entity has been manually annotated by the ChEBI Team.

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Formula

C24H26ClNO4

Net Charge

Average Mass

427.92100

Monoisotopic Mass

427.15504

InChI

InChI=1S/C24H25NO4.ClH/c1-17-21(26)19-11-8-12-20(23(19)29-22(17)18-9-4-2-5-10-18)24(27)28-16-15-25-13-6-3-7-14-25;/h2,4-5,8-12H,3,6-7,13-16H2,1H3;1H

InChIKey

XOEVKNFZUQEERE-UHFFFAOYSA-N

SMILES

Cl.Cc1c(oc2c(cccc2c1=O)C(=O)OCCN1CCCCC1)-c1ccccc1

Roles Classification
Biological Role(s):	parasympatholytic Any cholinergic antagonist that inhibits the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the muscarinic antagonists. muscarinic antagonist A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.

Application(s):	parasympatholytic Any cholinergic antagonist that inhibits the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the muscarinic antagonists. muscarinic antagonist A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists. antispasmodic drug A drug that suppresses spasms. These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder.

ChEBI Ontology
Outgoing	flavoxate hydrochloride (CHEBI:5089) has part flavoxate(1+) (CHEBI:61236) flavoxate hydrochloride (CHEBI:5089) has role antispasmodic drug (CHEBI:53784) flavoxate hydrochloride (CHEBI:5089) has role muscarinic antagonist (CHEBI:48876) flavoxate hydrochloride (CHEBI:5089) has role parasympatholytic (CHEBI:50370) flavoxate hydrochloride (CHEBI:5089) is a hydrochloride (CHEBI:36807)

IUPAC Name

1-(2-{[(3-methyl-4-oxo-2-phenyl-4H-chromen-8-yl)carbonyl]oxy}ethyl)piperidinium chloride

Synonyms	Sources
2-(piperidin-1-yl)ethyl 3-methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylate hydrochloride	IUPAC
2-piperidinoethyl 3-methyl-4-oxo-2-phenyl-4H-1-benzopyran-8-carboxylate hydrochloride	ChemIDplus
flavoxate HCl	ChemIDplus

Brand Name	Source
Urispas	KEGG DRUG

Last Modified

04 February 2013

General Comment
2011-02-04	A smooth muscle relaxant but with antimuscarinic effects, flavoxate hydrochloride is used for the symptomatic relief of pain, urinary frequency, and incontinence associated with inflammatory disorders of the urinary tract, as well as for relief of vesico-urethral spasms resulting from instrumentation or surgery.