CHEBI:5134 - fluticasone

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ChEBI Name fluticasone ChEBI ID CHEBI:5134 Definition A trifluorinated corticosteroid used in the form of its propionate ester for treatment of allergic rhinitis. Stars This entity has been manually annotated by the ChEBI Team. Supplier Information Download Molfile XML SDF Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search Wikipedia License Read full article at Wikipedia Formula C22H27F3O4S Net Charge 0 Average Mass 444.50800 Monoisotopic Mass 444.15822 InChI InChI=1S/C22H27F3O4S/c1-11-6-13-14-8-16(24)15-7-12(26)4-5-19(15,2)21(14,25)17(27)9-20(13,3)22(11,29)18(28)30-10-23/h4-5,7,11,13-14,16-17,27,29H,6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19+,20+,21+,22+/m1/s1 InChIKey MGNNYOODZCAHBA-GQKYHHCASA-N SMILES [H][C@@]12C[C@@H](C)[C@](O)(C(=O)SCF)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C Roles Classification Application(s): anti-asthmatic drug A drug used to treat asthma. anti-allergic agent A drug used to treat allergic reactions. View more via ChEBI Ontology ChEBI Ontology Outgoing fluticasone (CHEBI:5134) has parent hydride androstane (CHEBI:35509) fluticasone (CHEBI:5134) has role anti-allergic agent (CHEBI:50857) fluticasone (CHEBI:5134) has role anti-asthmatic drug (CHEBI:49167) fluticasone (CHEBI:5134) is a 11β-hydroxy steroid (CHEBI:35346) fluticasone (CHEBI:5134) is a 17α-hydroxy steroid (CHEBI:35342) fluticasone (CHEBI:5134) is a 3-oxo-Δ4 steroid (CHEBI:47909) fluticasone (CHEBI:5134) is a corticosteroid (CHEBI:50858) fluticasone (CHEBI:5134) is a fluorinated steroid (CHEBI:50830) fluticasone (CHEBI:5134) is a thioester (CHEBI:51277) Incoming fluticasone furoate (CHEBI:74899) has functional parent fluticasone (CHEBI:5134) fluticasone propionate (CHEBI:31441) has functional parent fluticasone (CHEBI:5134) IUPAC Name S-(fluoromethyl) (6α,11β,16α,17α)-6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carbothioate INNs Sources fluticasona ChemIDplus fluticasone WHO MedNet fluticasone KEGG DRUG fluticasonum ChemIDplus Manual Xrefs Databases C07815 KEGG COMPOUND D07981 KEGG DRUG Fluticasone Wikipedia View more database links Registry Numbers Types Sources 8173308 Reaxys Registry Number Reaxys 90566-53-3 CAS Registry Number KEGG COMPOUND 90566-53-3 CAS Registry Number ChemIDplus Citations Types Sources 22370858 PubMed citation Europe PMC 23276699 PubMed citation Europe PMC 23591272 PubMed citation Europe PMC 23796052 PubMed citation Europe PMC Last Modified 06 September 2013