CHEBI:59936 - ciprofloxacin hydrochloride hydrate

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ChEBI Name ciprofloxacin hydrochloride hydrate
ChEBI ID CHEBI:59936
Definition The monohydrate form of ciprofloxacin monohydrochloride.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Formula C17H21ClFN3O4
Net Charge 0
Average Mass 385.81800
Monoisotopic Mass 385.12046
InChI InChI=1S/C17H18FN3O3.ClH.H2O/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;;/h7-10,19H,1-6H2,(H,23,24);1H;1H2
InChIKey ARPUHYJMCVWYCZ-UHFFFAOYSA-N
SMILES O.Cl.OC(=O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O
Roles Classification
Biological Role(s): EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (also known as topoisomerase II and as DNA gyrase), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands.
antibacterial drug
A drug used to treat or prevent bacterial infections.
topoisomerase IV inhibitor
A topoisomerase inhibitor that inhibits DNA topoisomerase IV, which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands.
Application(s): antibacterial drug
A drug used to treat or prevent bacterial infections.
antiinfective agent
A substance used in the prophylaxis or therapy of infectious diseases.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing ciprofloxacin hydrochloride hydrate (CHEBI:59936) has part ciprofloxacin hydrochloride (anhydrous) (CHEBI:310388)
ciprofloxacin hydrochloride hydrate (CHEBI:59936) has role antibacterial drug (CHEBI:36047)
ciprofloxacin hydrochloride hydrate (CHEBI:59936) has role antiinfective agent (CHEBI:35441)
ciprofloxacin hydrochloride hydrate (CHEBI:59936) has role EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor (CHEBI:50750)
ciprofloxacin hydrochloride hydrate (CHEBI:59936) has role topoisomerase IV inhibitor (CHEBI:53559)
ciprofloxacin hydrochloride hydrate (CHEBI:59936) is a hydrate (CHEBI:35505)
IUPAC Name
1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride—water (1/1)
Synonyms Sources
1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride hydrate ChEBI
1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride monohydrate ChEBI
ciprofloxacin hydrochloride ChemIDplus
Ciprofloxacin hydrochloride monohydrate KEGG COMPOUND
ciprofloxacin hydrochloride monohydrate ChEBI
ciprofloxacin monohydrochloride monohydrate ChEBI
Manual Xrefs Databases
C13993 KEGG COMPOUND
D02216 KEGG DRUG
DB00537 DrugBank
View more database links
Registry Numbers Types Sources
86393-32-0 CAS Registry Number KEGG DRUG
86393-32-0 CAS Registry Number ChemIDplus
Last Modified
28 July 2014