CHEBI:60348 - (R)-profenamine

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ChEBI Name (R)-profenamine
ChEBI ID CHEBI:60348
ChEBI ASCII Name (R)-profenamine
Definition The (R)-enantiomer of profenamine.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C19H24N2S
Net Charge 0
Average Mass 312.480
Monoisotopic Mass 312.16602
InChI InChI=1S/C19H24N2S/c1-4-20(5-2)15(3)14-21-16-10-6-8-12-18(16)22-19-13-9-7-11-17(19)21/h6-13,15H,4-5,14H2,1-3H3/t15-/m1/s1
InChIKey CDOZDBSBBXSXLB-OAHLLOKOSA-N
SMILES N1(C2=C(SC3=C1C=CC=C3)C=CC=C2)C[C@H](N(CC)CC)C
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
(via profenamine )
histamine antagonist
Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.
(via profenamine )
adrenergic antagonist
An agent that binds to but does not activate adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists.
(via profenamine )
Application(s): muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
(via profenamine )
antiparkinson drug
A drug used in the treatment of Parkinson's disease.
(via profenamine )
histamine antagonist
Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.
(via profenamine )
adrenergic antagonist
An agent that binds to but does not activate adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists.
(via profenamine )
antidyskinesia agent
Any compound which can be used to treat or alleviate the symptoms of dyskinesia.
(via profenamine )
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ChEBI Ontology
Outgoing (R)-profenamine (CHEBI:60348) is a profenamine (CHEBI:313639)
(R)-profenamine (CHEBI:60348) is enantiomer of (S)-profenamine (CHEBI:60349)
Incoming (S)-profenamine (CHEBI:60349) is enantiomer of (R)-profenamine (CHEBI:60348)
IUPAC Name
(2R)-N,N-diethyl-1-(10H-phenothiazin-10-yl)propan-2-amine
Synonyms Sources
(αR)-N,N-diethyl-α-methyl-10H-phenothiazine ChEBI
(R)-ethopropazine ChEBI
Manual Xref Database
BUW PDBeChem
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Last Modified
21 November 2019