CHEBI:63449 - SU5402

Main

ChEBI Ontology

Automatic Xrefs

Reactions

Pathways

Models

ChEBI Name SU5402 ChEBI ID CHEBI:63449 Definition An oxindole that is 3-methyleneoxindole in which one of the hydrogens of the methylene group is substituted by a 3-(2-carboxyethyl)-4-methyl-1H-pyrrol-2-yl group. It is an ATP-competitive inhibitor of the tyrosine kinase activity of fibroblast growth factor receptor 1. Stars This entity has been manually annotated by the ChEBI Team. Submitter Bijay Supplier Information Download Molfile XML SDF Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search Formula C17H16N2O3 Net Charge 0 Average Mass 296.32050 Monoisotopic Mass 296.11609 InChI InChI=1S/C17H16N2O3/c1-10-9-18-15(11(10)6-7-16(20)21)8-13-12-4-2-3-5-14(12)19-17(13)22/h2-5,8-9,18H,6-7H2,1H3,(H,19,22)(H,20,21) InChIKey JNDVEAXZWJIOKB-UHFFFAOYSA-N SMILES [H]C(c1[nH]cc(C)c1CCC(O)=O)=C1C(=O)Nc2ccccc12 Roles Classification Chemical Role(s): Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Bronsted base). (via oxoacid ) Biological Role(s): fibroblast growth factor receptor antagonist An antagonist at the fibroblast growth factor receptor. View more via ChEBI Ontology ChEBI Ontology Outgoing SU5402 (CHEBI:63449) has functional parent 3-methyleneoxindole (CHEBI:17920) SU5402 (CHEBI:63449) has role fibroblast growth factor receptor antagonist (CHEBI:63457) SU5402 (CHEBI:63449) is a monocarboxylic acid (CHEBI:25384) SU5402 (CHEBI:63449) is a oxindoles (CHEBI:38459) SU5402 (CHEBI:63449) is a pyrroles (CHEBI:26455) IUPAC Name 3-{4-methyl-2-[(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl}propanoic acid Synonyms Sources 3-[3-(2-carboxyethyl)-4-methylpyrrol-2-methylidenyl]-2-indolinone SUBMITTER 3-{[3-(2-carboxyethyl)-4-methylpyrrol-2-yl]methylene}-2-indolinone ChEBI SU 5402 ChEBI Su-5402 ChEBI SU-5402 ChEBI Registry Number Type Source 8004406 Reaxys Registry Number Reaxys Last Modified 22 May 2012