CHEBI:64358 - rivastigmine tartrate

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ChEBI Name rivastigmine tartrate
ChEBI ID CHEBI:64358
Definition A tartrate salt obtained by reaction of rivastigmine with one equivalent of (R,R)-tartaric acid. A reversible cholinesterase inhibitor.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Anonymous
Supplier Information ChemicalBook:CB9500851, ChemicalBook:CB8328151, eMolecules:11312351, Selleckchem:rivastigmine-tartrate-exelon
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Formula C18H28N2O8
Net Charge 0
Average Mass 400.42350
Monoisotopic Mass 400.18457
InChI InChI=1S/C14H22N2O2.C4H6O6/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4;5-1(3(7)8)2(6)4(9)10/h7-11H,6H2,1-5H3;1-2,5-6H,(H,7,8)(H,9,10)/t11-;1-,2-/m01/s1
InChIKey GWHQHAUAXRMMOT-MBANBULQSA-N
SMILES O[C@H]([C@@H](O)C(O)=O)C(O)=O.CCN(C)C(=O)Oc1cccc(c1)[C@H](C)N(C)C
Roles Classification
Biological Role(s): cholinergic drug
Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons.
EC 3.1.1.8 (cholinesterase) inhibitor
An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of cholinesterase (EC 3.1.1.8).
Application(s): cholinergic drug
Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons.
neuroprotective agent
Any compound that can be used for the treatment of neurodegenerative disorders.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing rivastigmine tartrate (CHEBI:64358) has part rivastigmine(1+) (CHEBI:64363)
rivastigmine tartrate (CHEBI:64358) has role cholinergic drug (CHEBI:38323)
rivastigmine tartrate (CHEBI:64358) has role EC 3.1.1.8 (cholinesterase) inhibitor (CHEBI:37733)
rivastigmine tartrate (CHEBI:64358) has role neuroprotective agent (CHEBI:63726)
rivastigmine tartrate (CHEBI:64358) is a tartrate salt (CHEBI:50562)
IUPAC Name
3-[(1S)-1-(dimethylamino)ethyl]phenyl ethyl(methyl)carbamate (2R,3R)-2,3-dihydroxybutanedioate
Synonyms Sources
(1S)-1-(3-{[ethyl(methyl)carbamoyl]oxy}phenyl)-N,N-dimethylethanaminium (2R,3R)-3-carboxy-2,3-dihydroxypropanoate IUPAC
rivastigmine hydrogen tartrate DrugBank
SDZ-ENA 713 ChemIDplus
Brand Name Source
Exelon KEGG DRUG
Manual Xrefs Databases
D02558 KEGG DRUG
DB00989 DrugBank
EP1980552 Patent
EP2233465 Patent
US2008255383 Patent
US2008306280 Patent
View more database links
Registry Numbers Types Sources
129101-54-8 CAS Registry Number KEGG DRUG
129101-54-8 CAS Registry Number ChemIDplus
9305032 Reaxys Registry Number Reaxys
Citations Waiting for Citations
Last Modified
11 April 2012