CHEBI:64920 - EC 6.5.1.1 [DNA ligase (ATP)] inhibitor

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name EC 6.5.1.1 [DNA ligase (ATP)] inhibitor
ChEBI ID CHEBI:64920
Definition An EC 6.5.1.* (DNA/RNA repair enzymes) inhibitor that interferes with the action of DNA ligase (ATP), EC 6.5.1.1.
Stars This entity has been manually annotated by the ChEBI Team.
Wikipedia License
DNA ligase is a type of enzyme that facilitates the joining of DNA strands together by catalyzing the formation of a phosphodiester bond. It plays a role in repairing single-strand breaks in duplex DNA in living organisms, but some forms (such as DNA ligase IV) may specifically repair double-strand breaks (i.e. a break in both complementary strands of DNA). Single-strand breaks are repaired by DNA ligase using the complementary strand of the double helix as a template, with DNA ligase creating the final phosphodiester bond to fully repair the DNA. DNA ligase is used in both DNA repair and DNA replication (see Mammalian ligases). In addition, DNA ligase has extensive use in molecular biology laboratories for recombinant DNA experiments (see Research applications). Purified DNA ligase is used in gene cloning to join DNA molecules together to form recombinant DNA.
Read full article at Wikipedia
ChEBI Ontology
Outgoing EC 6.5.1.1 [DNA ligase (ATP)] inhibitor (CHEBI:64920) is a EC 6.5.1.* (DNA/RNA repair enzymes) inhibitor (CHEBI:76827)
Incoming swertifrancheside (CHEBI:66537) has role EC 6.5.1.1 [DNA ligase (ATP)] inhibitor (CHEBI:64920)
Synonyms Sources
deoxyribonucleate ligase inhibitor ChEBI
deoxyribonucleate ligase inhibitors ChEBI
deoxyribonucleic acid joinase inhibitor ChEBI
deoxyribonucleic acid joinase inhibitors ChEBI
deoxyribonucleic acid ligase inhibitor ChEBI
deoxyribonucleic acid ligase inhibitors ChEBI
deoxyribonucleic acid repair enzyme inhibitor ChEBI
deoxyribonucleic acid repair enzyme inhibitors ChEBI
deoxyribonucleic acid-joining enzyme inhibitor ChEBI
deoxyribonucleic acid-joining enzyme inhibitors ChEBI
deoxyribonucleic joinase inhibitor ChEBI
deoxyribonucleic joinase inhibitors ChEBI
deoxyribonucleic ligase inhibitor ChEBI
deoxyribonucleic ligase inhibitors ChEBI
deoxyribonucleic repair enzyme inhibitor ChEBI
deoxyribonucleic repair enzyme inhibitors ChEBI
deoxyribonucleic-joining enzyme inhibitor ChEBI
deoxyribonucleic-joining enzyme inhibitors ChEBI
DNA joinase inhibitor ChEBI
DNA joinase inhibitors ChEBI
DNA ligase (ATP) (EC 6.5.1.1) inhibitor ChEBI
DNA ligase (ATP) (EC 6.5.1.1) inhibitors ChEBI
DNA ligase (ATP) inhibitor ChEBI
DNA ligase inhibitor ChEBI
DNA ligase inhibitors ChEBI
DNA repair enzyme inhibitor ChEBI
DNA repair enzyme inhibitors ChEBI
DNA-joining enzyme inhibitor ChEBI
DNA-joining enzyme inhibitors ChEBI
EC 6.5.1.1 (DNA ligase (ATP)) inhibitor ChEBI
EC 6.5.1.1 (DNA ligase (ATP)) inhibitors ChEBI
EC 6.5.1.1 [DNA ligase (ATP)] inhibitors ChEBI
EC 6.5.1.1 inhibitor ChEBI
EC 6.5.1.1 inhibitors ChEBI
polydeoxyribonucleotide synthase (ATP) inhibitor ChEBI
sealase inhibitor ChEBI
sealase inhibitors ChEBI
Manual Xref Database
Dna_Ligase Wikipedia
View more database links
Last Modified
10 January 2014