CHEBI:66064 - 10-hydroxycanthin-6-one

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ChEBI Name 10-hydroxycanthin-6-one
ChEBI ID CHEBI:66064
Definition An indole alkaloid that is canthin-6-one substituted by a hydroxy group at position 10. Isolated from Simaba multiflora, it exhibits antineoplastic activity.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C14H8N2O2
Net Charge 0
Average Mass 236.22550
Monoisotopic Mass 236.05858
InChI InChI=1S/C14H8N2O2/c17-8-1-3-12-10(7-8)9-5-6-15-11-2-4-13(18)16(12)14(9)11/h1-7,17H
InChIKey FZLISVGXWLVEPB-UHFFFAOYSA-N
SMILES Oc1ccc2c(c1)c1ccnc3ccc(=O)n2c13
Metabolite of Species Details
Simaba multiflora (IPNI:236532-2) Found in xylem (BTO:0001468). Previous component: wood; See: PubMed
Roles Classification
Biological Role(s): metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via alkaloid )
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing 10-hydroxycanthin-6-one (CHEBI:66064) has functional parent canthin-6-one (CHEBI:3363)
10-hydroxycanthin-6-one (CHEBI:66064) has role antineoplastic agent (CHEBI:35610)
10-hydroxycanthin-6-one (CHEBI:66064) has role metabolite (CHEBI:25212)
10-hydroxycanthin-6-one (CHEBI:66064) is a indole alkaloid (CHEBI:38958)
10-hydroxycanthin-6-one (CHEBI:66064) is a organic heterotetracyclic compound (CHEBI:38163)
IUPAC Name
10-hydroxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one
Synonym Source
ervine ChEBI
Manual Xref Database
139791 ChemSpider
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Registry Numbers Types Sources
5340157 Reaxys Registry Number Reaxys
86293-41-6 CAS Registry Number ChemIDplus
Citation Waiting for Citations Type Source
6875577 PubMed citation Europe PMC
Last Modified
07 November 2013