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ChEBI
> Main
CHEBI:66064 - 10-hydroxycanthin-6-one
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ChEBI Name
10-hydroxycanthin-6-one
ChEBI ID
CHEBI:66064
Definition
An indole alkaloid that is canthin-6-one substituted by a hydroxy group at position 10. Isolated from
Simaba multiflora
, it exhibits antineoplastic activity.
Stars
This entity has been manually annotated by the ChEBI Team.
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Formula
C14H8N2O2
Net Charge
0
Average Mass
236.22550
Monoisotopic Mass
236.05858
InChI
InChI=1S/C14H8N2O2/c17-8-1-3-12-10(7-8)9-5-6-15-11-2-4-13(18)16(12)14(9)11/h1-7,17H
InChIKey
FZLISVGXWLVEPB-UHFFFAOYSA-N
SMILES
Oc1ccc2c(c1)c1ccnc3ccc(=O)n2c13
Metabolite of Species
Details
Simaba multiflora
(IPNI:236532-2)
Found in xylem
(BTO:0001468)
. Previous component: wood; See:
PubMed
Roles Classification
Biological Role
(s):
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via
alkaloid
)
Application
(s):
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
10-hydroxycanthin-6-one (
CHEBI:66064
)
has functional parent
canthin-6-one (
CHEBI:3363
)
10-hydroxycanthin-6-one (
CHEBI:66064
)
has role
antineoplastic agent (
CHEBI:35610
)
10-hydroxycanthin-6-one (
CHEBI:66064
)
has role
metabolite (
CHEBI:25212
)
10-hydroxycanthin-6-one (
CHEBI:66064
)
is a
indole alkaloid (
CHEBI:38958
)
10-hydroxycanthin-6-one (
CHEBI:66064
)
is a
organic heterotetracyclic compound (
CHEBI:38163
)
IUPAC Name
10-hydroxy-6
H
-indolo[3,2,1-
de
][1,5]naphthyridin-6-one
Synonym
Source
ervine
ChEBI
Manual Xref
Database
139791
ChemSpider
View more database links
Registry Numbers
Types
Sources
5340157
Reaxys Registry Number
Reaxys
86293-41-6
CAS Registry Number
ChemIDplus
Citation
Type
Source
6875577
PubMed citation
Europe PMC
Last Modified
07 November 2013