Services
Research
Training
Industry
About us
ChEBI
Examples:
iron*
,
InChI=1S/CH4O/c1-2/h2H,1H3
,
caffeine
Advanced
Home
Advanced Search
Browse
Documentation
Download
Tools
About ChEBI
Submit
Contact us
DiNA
Statistics
Entity of the Month
Periodic Table
Ontology
Train online
User Manual
Annotation Manual
Developer Manual
FAQ's
BiNChE
libChEBI
Web Services
ChEBI
> Main
CHEBI:67272 - perifosine
Main
ChEBI Ontology
Automatic Xrefs
Reactions
Pathways
Models
ChEBI Name
perifosine
ChEBI ID
CHEBI:67272
Definition
A phospholipid consisting of 1,1-dimethylpiperidinium-4-yl hydrogen phosphate in which the hydrogen is replaced by a stearyl (octadecyl) group.
Stars
This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download
Molfile
XML
SDF
Find compounds which contain this structure
Find compounds which resemble this structure
Take structure to the Advanced Search
Wikipedia
License
Read full article at Wikipedia
Formula
C25H52NO4P
Net Charge
0
Average Mass
461.65840
Monoisotopic Mass
461.36340
InChI
InChI=1S/C25H52NO4P/c1-
4-
5-
6-
7-
8-
9-
10-
11-
12-
13-
14-
15-
16-
17-
18-
19-
24-
29-
31(27,28)
30-
25-
20-
22-
26(2,3)
23-
21-
25/h25H,4-
24H2,1-
3H3
InChIKey
SZFPYBIJACMNJV-UHFFFAOYSA-N
SMILES
CCCCCCCCCCCCCCCCCCOP([O-])(=O)OC1CC[N+](C)(C)CC1
Roles Classification
Biological Role
(s):
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
An inhibitor of phosphatidylinositol 3-kinase, EC 2.7.1.137, a family of related enzymes capable of phosphorylating the 3 position hydroxy group of the inositol ring of a phosphatidylinositol.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
perifosine (
CHEBI:67272
)
has functional parent
octadecan-1-ol (
CHEBI:32154
)
perifosine (
CHEBI:67272
)
has role
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor (
CHEBI:50914
)
perifosine (
CHEBI:67272
)
is a
ammonium betaine (
CHEBI:35284
)
perifosine (
CHEBI:67272
)
is a
phospholipid (
CHEBI:16247
)
IUPAC Name
1,1-dimethylpiperidinium-4-yl octadecyl phosphate
Synonym
Source
KRX-0401
ChemIDplus
Manual Xref
Database
Perifosine
Wikipedia
View more database links
Registry Numbers
Types
Sources
11186113
Reaxys Registry Number
Reaxys
157716-52-4
CAS Registry Number
ChemIDplus
Citation
Type
Source
22512706
PubMed citation
Europe PMC
Last Modified
25 September 2012