dihydrooroxylin A (CHEBI:67376)

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ChEBI Name	dihydrooroxylin A

ChEBI ID	CHEBI:67376

Definition	A dihydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5 and 7 and a methoxy group at position 6. Isolated from Pisonia aculeata, it exhibits antitubercular activity.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formula

C16H14O5

Net Charge

Average Mass

286.27940

Monoisotopic Mass

286.08412

InChI

InChI=1S/C16H14O5/c1-20-16-11(18)8-13-14(15(16)19)10(17)7-12(21-13)9-5-3-2-4-6-9/h2-6,8,12,18-19H,7H2,1H3

InChIKey

QUAPPCXFYKSDSV-UHFFFAOYSA-N

SMILES

COc1c(O)cc2OC(CC(=O)c2c1O)c1ccccc1

Metabolite of Species	Details
Pisonia aculeata (NCBI:txid363212)	Found in stem (BTO:0001300). Cold methanolic extract of dried stems and roots See: PubMed
Pisonia aculeata (NCBI:txid363212)	Found in root (BTO:0001188). Cold methanolic extract of dried stems and roots See: PubMed

Roles Classification
Biological Role(s):	antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. plant metabolite Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.

Application(s):	antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis.

ChEBI Ontology
Outgoing	dihydrooroxylin A (CHEBI:67376) has role antitubercular agent (CHEBI:33231) dihydrooroxylin A (CHEBI:67376) has role plant metabolite (CHEBI:76924) dihydrooroxylin A (CHEBI:67376) is a dihydroxyflavanone (CHEBI:38749) dihydrooroxylin A (CHEBI:67376) is a monomethoxyflavanone (CHEBI:38738)

IUPAC Name

5,7-dihydroxy-6-methoxy-2-phenyl-2,3-dihydro-4H-chromen-4-one

Synonym	Source
5,7-dihydroxy-6-methoxyflavanone	ChEBI

Registry Number	Type	Source
294379	Reaxys Registry Number	Reaxys

Last Modified

09 January 2014