methaqualone (CHEBI:6821)

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ChEBI Name	methaqualone

ChEBI ID	CHEBI:6821

Definition	A member of the class of quinazolines that is quinazolin-4-one substituted at positions 2 and 3 by methyl and o-tolyl groups respectively. A depressant that increases the activity of the GABA receptors in the brain and nervous system, it is used as a sedative and hypnotic medication. It became popular as a recreational drug and club drug in the late 1960s and 1970s.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

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Formula

C16H14N2O

Net Charge

Average Mass

250.296

Monoisotopic Mass

250.11061

InChI

InChI=1S/C16H14N2O/c1-11-7-3-6-10-15(11)18-12(2)17-14-9-5-4-8-13(14)16(18)19/h3-10H,1-2H3

InChIKey

JEYCTXHKTXCGPB-UHFFFAOYSA-N

SMILES

N1(C=2C(=CC=CC2)C)C(C3=C(C=CC=C3)N=C1C)=O

Roles Classification
Biological Role(s):	GABA agonist A drug that binds to and activates gamma-aminobutyric acid receptors.

Application(s):	GABA agonist A drug that binds to and activates gamma-aminobutyric acid receptors. sedative A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.

ChEBI Ontology
Outgoing	methaqualone (CHEBI:6821) has role GABA agonist (CHEBI:51373) methaqualone (CHEBI:6821) has role sedative (CHEBI:35717) methaqualone (CHEBI:6821) is a quinazolines (CHEBI:38530)

IUPAC Name

2-methyl-3-(2-methylphenyl)quinazolin-4(3H)-one

Registry Number	Type	Source
72-44-6	CAS Registry Number	ChemIDplus

Last Modified

19 June 2017