CHEBI:76406 - cis-diammine[d(pGpG)]platinum

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ChEBI Name cis-diammine[d(pGpG)]platinum ChEBI ID CHEBI:76406 ChEBI ASCII Name cis-diammine[d(pGpG)]platinum Definition A cisplatin-modified (di)nucleotide in which cisplatin has formed an adduct with one molecule of d(pGpG), coordinated to platinum through the N7 atoms of both guanine moieties. Stars This entity has been manually annotated by the ChEBI Team. Supplier Information Download Molfile XML SDF Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search Formula C20H32N12O13P2Pt Net Charge 0 Average Mass 905.57200 Monoisotopic Mass 905.13350 InChI InChI=1S/C20H26N10O13P2.2H3N.Pt/c21-19-25-15-13(17(32)27-19)23-5-29(15)11-1-7(31)9(41-11)3-40-45(37,38)43-8-2-12(42-10(8)4-39-44(34,35)36)30-6-24-14-16(30)26-20(22)28-18(14)33;;;/h5-12,31H,1-4H2,(H,37,38)(H2,34,35,36)(H3,21,25,27,32)(H3,22,26,28,33);2*1H3;/t7-,8-,9+,10+,11+,12+;;;/m0.../s1 InChIKey IDHDKQFZBZWDHS-UAICMQSMSA-N SMILES Nc1nc2N3C=[N](c2c(=O)[nH]1)[Pt](N)(N)[N]1=CN([C@H]2C[C@H](O)[C@@H](COP(O)(=O)O[C@H]4C[C@H]3O[C@@H]4COP(O)(O)=O)O2)c2nc(N)[nH]c(=O)c12 ChEBI Ontology Outgoing cis-diammine[d(pGpG)]platinum (CHEBI:76406) has part 5'-d(pGpG)-3' (CHEBI:76403) cis-diammine[d(pGpG)]platinum (CHEBI:76406) is a cisplatin-modified (di)nucleotide (CHEBI:76397) IUPAC Name (SP-4-2)-{[5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl-κN7)-3-{[{[5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl-κN7)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}-4-hydroxytetrahydrofuran-2-yl]methyl dihydrogen phosphate}(diammine)platinum Synonyms Sources cis-diammine{2'-deoxyguanylyl-(5'→3')-2'-deoxy-5'-guanylic acid[κ2N7(1),N7(2)]}platinum ChEBI cis-Pt(NH3)2[d(pGpG)-N7(1),N7(2)] ChEBI Citation Type Source 1855275 PubMed citation Europe PMC Last Modified 25 November 2013