CHEBI:77602 - (3R,5S)-fluvastatin sodium

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ChEBI Name (3R,5S)-fluvastatin sodium
ChEBI ID CHEBI:77602
ChEBI ASCII Name (3R,5S)-fluvastatin sodium
Definition An organic sodium salt resulting from the replacement of the proton from the carboxy group of (3R,5S)-fluvastatin by a sodium ion.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C24H25FNNaO4
Net Charge 0
Average Mass 433.44780
Monoisotopic Mass 433.16653
InChI InChI=1S/C24H26FNO4.Na/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30;/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30);/q;+1/p-1/b12-11+;/t18-,19-;/m1./s1
InChIKey ZGGHKIMDNBDHJB-NRFPMOEYSA-M
SMILES [Na+].CC(C)n1c(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(-c2ccc(F)cc2)c2ccccc12
Roles Classification
Biological Role(s): EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor
Any EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD+ or NADP+ acceptor) inhibitor that inhibits HMG-CoA reductases. Hydroxymethylglutaryl-CoA reductase inhibitors have been shown to lower directly cholesterol synthesis. The Enzyme Commission designation is EC 1.1.1.34 for the NADPH-dependent enzyme and EC 1.1.1.88 for an NADH-dependent enzyme.
(via statin )
Application(s): anticholesteremic drug
A substance used to lower plasma cholesterol levels.
(via statin )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing (3R,5S)-fluvastatin sodium (CHEBI:77602) has part (3R,5S)-fluvastatin(1−) (CHEBI:77600)
(3R,5S)-fluvastatin sodium (CHEBI:77602) is a organic sodium salt (CHEBI:38700)
(3R,5S)-fluvastatin sodium (CHEBI:77602) is a statin (synthetic) (CHEBI:87635)
(3R,5S)-fluvastatin sodium (CHEBI:77602) is enantiomer of (3S,5R)-fluvastatin sodium (CHEBI:77603)
Incoming fluvastatin sodium (CHEBI:5137) has part (3R,5S)-fluvastatin sodium (CHEBI:77602)
(3S,5R)-fluvastatin sodium (CHEBI:77603) is enantiomer of (3R,5S)-fluvastatin sodium (CHEBI:77602)
IUPAC Name
sodium (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate
Synonyms Sources
(+)-(3R,5S)-fluvastatin sodium ChEBI
(+)-fluvastatin sodium ChEBI
(3R,5S)-(+)-fluvastatin sodium ChEBI
Registry Number Type Source
4286607 Reaxys Registry Number Reaxys
Last Modified
24 August 2015