Any of a family of steroid acids derived from sterols by oxidation with a cytochrome p450 that bind and activate the orphan nuclear receptor DAF-12 in the nematode Caenorhabditis elegans. Note that the singular term 'dafachronic acid' has been used as a synonym for the (non-natural) fully saturated (5α,25S)-3-oxocholestan-26-oic acid.
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This entity has been manually annotated by the ChEBI Team.
Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds.
